Protein Alignment ChAT and T20B3.1

DIOPT Version :9

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001360572.1
• Gene: T20B3.1 / 180126
• WormBaseID: WBGene00011850
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 687
• Identity: 168/687 - (24%)
• Similarity: 294/687 - (42%)
• Gaps: 135/687 - (19%)

  Fly    82 FGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLHQYLLDKREA 146
            |...|.||.:|||:|.||:..||.:...|.|||:..|.::...:|...: :||:|...|.::.:.
 Worm     4 FSRQDQLPSLPVPSLVETLEKYIDSASAILTPAEKARVEKEAHEFQHSE-LGAQLQSALENRAKN 67

  Fly   147 EDNWAYYYWLNEMYMDIRIPL-PINSNPGMVFPPRRFKTVHDV-----AHFAARLLDGILSHREM 205
            ..||...:|.| .|.:||.|| |..|...|       .|.::.     ...||.:|...||..:.
 Worm    68 HKNWLEDWWYN-AYTEIREPLAPYVSFGAM-------NTAYNCVDGGQVSRAADVLHHWLSVWDK 124

  Fly   206 LDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDS--QFLPSRERLNDEDRHVVVICRN 268
            :..|:.|:    :..:.....|.|::.|..|.|.|...:|:  ::..::|. .|...||::.|..
 Worm   125 VRHGKWPV----TSSRGVTWDMQQFHHLFSSNRTPQRTRDTMDRYFKTKEE-GDTPTHVIICCDG 184

  Fly   269 QMYCV-VLQASDRGKLSESEIASQILYV----LSDAPCLPAKPVPVGLLTAEPRSTWARDR-EML 327
            ..:.: :|...|....|..||.:.:.:|    ..::.|..:|      ||...|..|:.:| |:|
 Worm   185 CFWKLNILNEDDDTIKSPDEIYNMLKFVRDNSSDESSCCVSK------LTTTNRDVWSLNRDELL 243

  Fly   328 QEDERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEY 392
            :....|...:..:||:.:.|.:                  ...:.||..:..|::.:      :.
 Worm   244 RVSSANIEYVRAVETSILFLSM------------------VPKKGGDDQQKLMSNAL------QD 284

  Fly   393 NSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEE---HPDEDNGLPQHHLP 454
            .|...|.||::.:.|..|....:..:||..:.|.::|:.:.:..::.:   ||.:...  ..|..
 Worm   285 ESWFVWQDKSVNITIYEDAQVMVQGDHSNIDAIVLLQVGDYVASRVRKQLWHPAKTGS--DLHFE 347

  Fly   455 PPERLEWHVGPQLQ--LRFAQASKSVDKCIDDLDFY----VYR-----YQSYGKTFIKSCQVSPD 508
            .||||.:.....|:  :.||           |::||    :||     :..||....::.:|..|
 Worm   348 FPERLIFEFNEPLRHAISFA-----------DVEFYKSKQLYRARGVHHHGYGNELCRTAKVYTD 401

  Fly   509 VYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESD 573
            ..:|||||||..|.:|.....||:||||:|.|||.:.:|..:::.:.:|||:.    .:..:.::
 Worm   402 TVVQLALQLAFLKTHGSFAPIYETASTRKFFHGRTETVRGCTSQFVRFAKALL----GDQTVANE 462

  Fly   574 REDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKNILGNGIDIPLLGLR-EASIEVTG---- 633
            :||                |::||..|:....::|...:.|.|.|..|:||: ..||...|
 Worm   463 KED----------------LKKLFDSAINAHNQLMADCMDGRGFDRHLMGLKLTLSIMNKGCGPK 511

  Fly   634 -EMHELFKDESYIIS---QCFLLSTSQVACSTDSFMGY------------GPVTPRGYGCSYNPH 682
             :..|..:|:::..:   ..|||||        ||:||            ..:.|.||||.|...
 Worm   512 RQAPEFLRDDTWKRTGGDGNFLLST--------SFIGYMDGNQPGTFGYVAAMRPDGYGCFYRIG 568

  Fly   683 PEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLL 719
            ..:|...||.:.|.. ::...:..::..:||.:...|
 Worm   569 KSRISVAVSDWVSSR-SNIDAFCANILWALDALAPFL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	165/676 (24%)
T20B3.1	NP_001360572.1	Carn_acyltransf	10..598	CDD:376382	163/673 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920