Protein Alignment ChAT and chat

DIOPT Version :9

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_002933959.1
• Gene: chat / 100485221
• XenbaseID: XB-GENE-984174
• Length: 636
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 252/645 - (39%)
• Similarity: 376/645 - (58%)
• Gaps: 68/645 - (10%)

  Fly    88 LPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAY 152
            |||:|||.|.:||..|::.::.:.|..|.:::|.::..|..|.|.|..|.:.||::||..:||.:
 Frog    23 LPKLPVPPLKQTMDTYLKCMKHLVTEEQYQKSKAVVDAFMMPGGEGETLQEKLLERREKMENWIH 87

  Fly   153 YYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAA 217
            .|||::||::.|:|||:||:|.::|....|:..:|...|||.|:.|:|.::.||||..||::.|.
 Frog    88 LYWLDDMYLNNRLPLPVNSSPAVIFARHNFRDTNDQLRFAANLISGVLDYKTMLDSQALPVDFAR 152

  Fly   218 SREKNQPLCMAQYYRLLGSCRRPG------VKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQ 276
            .:...||:||.|||.|..|.|.||      |.|:|..:|       |..|::|.|.||.:.:.:.
 Frog   153 GQLSGQPMCMKQYYGLFSSYRLPGTIKDTLVAQESTIMP-------EPEHIIVACNNQFFVLDVV 210

  Fly   277 ASDRGKLSESEIASQILYV----LSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDERNQRNL 337
            .:.| :|||.::.:|:..:    .::...||    |:||||::.|:.||..||.|.:|..|:.:|
 Frog   211 INFR-RLSEGDLFTQLCKIDRMAKNEEEMLP----PIGLLTSDGRAEWAHARETLMKDSTNRDSL 270

  Fly   338 ELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKT 402
            ::||....::|||.|.....|                  :||.|.:::||||...|.||||:||.
 Frog   271 DMIERCMCIVCLDAPTKMELN------------------DTNRALQLLHGGGIGRNGGNRWYDKP 317

  Fly   403 MQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPDE----DNGLPQHHLPPPERLEWHV 463
            ||.::.:||..|...|||..:||.:||..|.:.|.::..|.:    |:   ...||.|.||.|..
 Frog   318 MQFVVGSDGVCGTICEHSPFDGIVLVQCTEHLLKYMKNSPKKLVRADS---VSELPAPRRLRWKC 379

  Fly   464 GPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVA 528
            .|::|...|.::..:.:.:::|||.||::::|||.|||..::|||.:||:|||||.|:.:.:||.
 Frog   380 SPEIQGHLASSANKLQRIVNNLDFIVYKFKNYGKEFIKKQRMSPDAFIQVALQLAFYRCHRKLVP 444

  Fly   529 TYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHL 593
            ||||||.|||..||||.||:::.|||.:..||..||.....:|.
 Frog   445 TYESASIRRFQMGRVDNIRSSTAEALAFVNAMVDGETTVTNIEK--------------------- 488

  Fly   594 RELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVA 658
            .|..|.|:..|||..::.|.|..||..||.|||.:.|...|:.|||:||.|:.|..|:||||||.
 Frog   489 MEYLRAAIKSQTEYTIQAITGMAIDNHLLALRELAQEHFKELPELFRDEMYLTSNRFILSTSQVP 553

  Fly   659 CSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDL 718
            .:.:.|..||||.|.||||.|||.||.|:||||:|:.|:|||:|::||::::||..|.||
 Frog   554 TTMEMFCCYGPVVPNGYGCCYNPQPEHILFCVSSFHDCKDTSSSKFAKAVEESLLAMGDL 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	249/641 (39%)
chat	XP_002933959.1	Carn_acyltransf	23..610	CDD:376382	249/640 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	453	1.000	Domainoid score	I498
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40693
Inparanoid	1	1.050	454	1.000	Inparanoid score	I1551
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm48143
Panther	1	1.100	-	-	LDO	PTHR22589
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160