Protein Alignment ChAT and chata

DIOPT Version :10

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001124191.1
• Gene: chata / 100170938
• ZFINID: ZDB-GENE-080102-2
• Length: 637
• Species: Danio rerio
• Alignment Length: 647
• Identity: 243/647 - (37%)
• Similarity: 359/647 - (55%)
• Gaps: 43/647 - (6%)

  Fly    73 LSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLH 137
            :|..|...:.|.|..|||:|:|.|.:|:..|:..:..:....|..:||.::.:|.||.|:|..|.
Zfish     3 VSKREQSKDTGDPCALPKLPIPPLKQTLDMYLTCMGHLVPEDQFRKTKAVVEKFGAPGGVGETLQ 67

  Fly   138 QYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSH 202
            :.||::.|.:.||.|.|||.:||::.|:.||:||:|.|||..:.||...||..|||.|:.|:|.:
Zfish    68 KKLLERSEQKANWVYDYWLEDMYLNNRLALPVNSSPVMVFHKQNFKGQSDVLRFAANLISGVLEY 132

  Fly   203 REMLDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICR 267
            :.::|...||:|.|..:....||||.||.::..|.|.||.|.|: .:..:..:..|..|::|.|:
Zfish   133 KALIDGRALPVEHARGQLAGTPLCMDQYNKVFTSYRLPGTKTDT-LVAQKSTVMPEPEHIIVACK 196

  Fly   268 NQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDER 332
            ||.:.:.:..:.| :|:|.::.:|:..:...|.....:..|:||||::.|:.||..|.:|.:|..
Zfish   197 NQFFVLDVMVNFR-RLNEKDLYTQLERIRKMADIEEERQPPIGLLTSDGRTQWAEARNILIKDST 260

  Fly   333 NQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNR 397
            |:.:|::||....::||||..|...|                  ::|.|..|:||||::.|.|||
Zfish   261 NRDSLDMIERCLCLVCLDEETATELN------------------DSNRALLMLHGGGTDKNGGNR 307

  Fly   398 WFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPDE-DNGLPQHHLPPPERLEW 461
            |:||.||.:|..||..|:..|||..|||.:||..|.:.:.:...|.: ........||.|.||.|
Zfish   308 WYDKPMQFVIGADGCCGVVCEHSPFEGIVLVQCSEYLLRYMRGSPSKLVRAASMSELPAPRRLRW 372

  Fly   462 HVGPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRL 526
            ...|.:|...:.::..:.|.:.:||..|:::..|||.|||..::|||.|:|:|||...|:.:|||
Zfish   373 KCSPDIQTFLSASADRLQKLVKNLDMNVHKFTGYGKEFIKRQKMSPDAYVQVALQFTFYRCHGRL 437

  Fly   527 VATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKD 591
            |.||||||.|||..||||.||:::.|||.:.|||..|        |...|.|:
Zfish   438 VPTYESASIRRFQEGRVDNIRSSTPEALAFVKAMASG--------SKITDAEK------------ 482

  Fly   592 HLRELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQ 656
              .||...|:..||...:..|.|..||..||||||.:.|:..|..|||.|.:|..|..|.|||||
Zfish   483 --MELLWTAIKAQTNYTILAITGMAIDNHLLGLREIAKELKLEKPELFSDTTYATSIHFTLSTSQ 545

  Fly   657 VACSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDL 718
            |..:.:.|..||||.|.|||..|||..:.|:||||:|..|.:||:..:.|:|:..|..|:||
Zfish   546 VPTTEEMFCCYGPVVPNGYGACYNPQTDHILFCVSSFRECAETSSDLFVKTLEGCLKEMQDL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	92..710	CDD:459926	232/618 (38%)
chata	NP_001124191.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/16 (31%)
		Carn_acyltransf	21..598	CDD:459926	231/618 (37%)