Protein Alignment ChAT and chata

DIOPT Version :9

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001124191.1
• Gene: chata / 100170938
• ZFINID: ZDB-GENE-080102-2
• Length: 637
• Species: Danio rerio
• Alignment Length: 647
• Identity: 243/647 - (37%)
• Similarity: 359/647 - (55%)
• Gaps: 43/647 - (6%)

  Fly    73 LSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLH 137
            :|..|...:.|.|..|||:|:|.|.:|:..|:..:..:....|..:||.::.:|.||.|:|..|.
Zfish     3 VSKREQSKDTGDPCALPKLPIPPLKQTLDMYLTCMGHLVPEDQFRKTKAVVEKFGAPGGVGETLQ 67

  Fly   138 QYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSH 202
            :.||::.|.:.||.|.|||.:||::.|:.||:||:|.|||..:.||...||..|||.|:.|:|.:
Zfish    68 KKLLERSEQKANWVYDYWLEDMYLNNRLALPVNSSPVMVFHKQNFKGQSDVLRFAANLISGVLEY 132

  Fly   203 REMLDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICR 267
            :.::|...||:|.|..:....||||.||.::..|.|.||.|.|: .:..:..:..|..|::|.|:
Zfish   133 KALIDGRALPVEHARGQLAGTPLCMDQYNKVFTSYRLPGTKTDT-LVAQKSTVMPEPEHIIVACK 196

  Fly   268 NQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDER 332
            ||.:.:.:..:.| :|:|.::.:|:..:...|.....:..|:||||::.|:.||..|.:|.:|..
Zfish   197 NQFFVLDVMVNFR-RLNEKDLYTQLERIRKMADIEEERQPPIGLLTSDGRTQWAEARNILIKDST 260

  Fly   333 NQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNR 397
            |:.:|::||....::||||..|...|                  ::|.|..|:||||::.|.|||
Zfish   261 NRDSLDMIERCLCLVCLDEETATELN------------------DSNRALLMLHGGGTDKNGGNR 307

  Fly   398 WFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPDE-DNGLPQHHLPPPERLEW 461
            |:||.||.:|..||..|:..|||..|||.:||..|.:.:.:...|.: ........||.|.||.|
Zfish   308 WYDKPMQFVIGADGCCGVVCEHSPFEGIVLVQCSEYLLRYMRGSPSKLVRAASMSELPAPRRLRW 372

  Fly   462 HVGPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRL 526
            ...|.:|...:.::..:.|.:.:||..|:::..|||.|||..::|||.|:|:|||...|:.:|||
Zfish   373 KCSPDIQTFLSASADRLQKLVKNLDMNVHKFTGYGKEFIKRQKMSPDAYVQVALQFTFYRCHGRL 437

  Fly   527 VATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKD 591
            |.||||||.|||..||||.||:::.|||.:.|||..|        |...|.|:
Zfish   438 VPTYESASIRRFQEGRVDNIRSSTPEALAFVKAMASG--------SKITDAEK------------ 482

  Fly   592 HLRELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQ 656
              .||...|:..||...:..|.|..||..||||||.:.|:..|..|||.|.:|..|..|.|||||
Zfish   483 --MELLWTAIKAQTNYTILAITGMAIDNHLLGLREIAKELKLEKPELFSDTTYATSIHFTLSTSQ 545

  Fly   657 VACSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDL 718
            |..:.:.|..||||.|.|||..|||..:.|:||||:|..|.:||:..:.|:|:..|..|:||
Zfish   546 VPTTEEMFCCYGPVVPNGYGACYNPQTDHILFCVSSFRECAETSSDLFVKTLEGCLKEMQDL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	236/628 (38%)
chata	NP_001124191.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/16 (31%)
		Carn_acyltransf	18..601	CDD:307070	235/624 (38%)
		Coenzyme A binding. /evidence=ECO:0000250	407..419		6/11 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594980
Domainoid	1	1.000	430	1.000	Domainoid score	I574
eggNOG	1	0.900	-	-		E1_KOG3717
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40693
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1648
OMA	1	1.010	-	-		QHG45782
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_107067
Panther	1	1.100	-	-	LDO	PTHR22589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2058
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800