DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ChT and LOC799259

DIOPT Version :9

Sequence 1:	NP_650743.1	Gene:	ChT / 42245	FlyBaseID:	FBgn0038641	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_001339635.2	Gene:	LOC799259 / 799259	-ID:	-	Length:	606	Species:	Danio rerio

Alignment Length:	593	Identity:	323/593 - (54%)
Similarity:	416/593 - (70%)	Gaps:	46/593 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 INIAGVVSIVLFYLLILVVGIWAGRKKQ-----SGNDSEEEVMLAGRSIGLFVGIFTMTATWVGG 61
            |::.|:::||:||||||:|||||..|.:     .|.|..|.:|:.||.||||||.||||||||||
Zfish    22 IHVEGLLAIVIFYLLILMVGIWAAWKNKHAGISEGTDRSETIMVGGRDIGLFVGGFTMTATWVGG 86

  Fly    62 GYINGTAEAIYT--SGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLL 124
            ||||||||::|.  .||.|.|||||||||||.||:|||.|||.:||:|||||.|..:|:||||||
Zfish    87 GYINGTAESVYVPGCGLAWAQAPFGYALSLVVGGLFFAKPMRSRGYVTMLDPFQQLYGQRMGGLL 151

  Fly   125 FLPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCI 189
            |:|||.||:||:|.||:|||||||||:|||...||::|:.||:||||.|||||||||||:|||||
Zfish   152 FIPALLGEIFWSAAILSALGATLSVIVDMDINMSVMISALIAVFYTLVGGLYSVAYTDVVQLFCI 216

  Fly   190 FIGLWMCIPFAWSNEHVGSLSDLEV---------DWIGHVEPKKHWLYIDYGLLLVFGGIPWQVY 245
            |:|||:.:|||.||.   ::||:.|         .|:|.:.|...|::.|...||:.||||||||
Zfish   217 FLGLWISVPFALSNP---AVSDIAVTAVKAVFQDPWLGEIHPSDGWMWADNFCLLMLGGIPWQVY 278

  Fly   246 FQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPLTVDETSMILPM 310
            ||||||:.:|..||:||::||.||::||:|.||||||..:|.||:|.|....|:..||:.||||:
Zfish   279 FQRVLSASSATYAQVLSFLAAFGCLVMAVPSVLIGAIGASTDWNQTSYGPVAPVDKDESDMILPI 343

  Fly   311 VLQYLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIV 375
            |||:|.|.|||||||||||||||||||||:|||:||||||:|:|.|||.||:.||:||||:.|.|
Zfish   344 VLQHLCPSFVSFFGLGAVSAAVMSSADSSILSASSMFARNIYQLAFRQSASDREIVWVMRITIFV 408

  Fly   376 VGILATIMALTIPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGE 440
            .|.:||.|||...|:||||.:.|||||||:|||||.|: |.|..|||||::.|:..|.:|:.|||
Zfish   409 FGAVATAMALLTGSVYGLWYLSSDLVYVIIFPQLLSVL-FIKGTNTYGSVAGYVFGLLLRIGGGE 472

  Fly   441 AILGLAPLIKYPGYDEETK------------EQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKL 493
            ..|.|.|.|.|||:....|            ||.||::|::||.||::..:.|:..|.:||||.|
Zfish   473 PYLRLPPFIYYPGWQMREKQHRLTQEVERFVEQRFPYKTVSMLASLLSNAAFSYLAKYLFESGTL 537

  Fly   494 PPSYDYFRCVV--NIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAG--------KDERNGR 548
            .|.||:...||  :..|.:.:....:.....||.::....|.  .:::||        :||  |.
Zfish   538 SPKYDFLDAVVSKHSKETMDKTTLVAHDTILLSELSAVKPRH--TSSLAGTFINADVLRDE--GS 598

  Fly   549 INPALESD 556
            ::|.||.:
Zfish   599 VSPDLEHE 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	297/501 (59%)
LOC799259	XP_001339635.2	SLC5sbd_CHT	27..525	CDD:271368	297/501 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	512	1.000	Domainoid score	I308
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32516
Inparanoid	1	1.050	603	1.000	Inparanoid score	I904
OMA	1	1.010	-	-		QHG62377
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004760
OrthoInspector	1	1.000	-	-		otm25079
orthoMCL	1	0.900	-	-		OOG6_104374
Panther	1	1.100	-	-	LDO	PTHR45897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3349
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.970