Protein Alignment ChT and slc5a3b

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_005167848.1
• Gene: slc5a3b / 568338
• ZFINID: ZDB-GENE-070912-43
• Length: 709
• Species: Danio rerio
• Alignment Length: 741
• Identity: 152/741 - (20%)
• Similarity: 260/741 - (35%)
• Gaps: 223/741 - (30%)

  Fly     5 AGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAE 69
            |.:..:.|:::|:||:|:.|..|  :.:.:.....||||::...|...::..:.:|..:..|.|.
Zfish    11 ADITVVALYFVLVLVIGLLAMWK--ANHSTVSGYFLAGRTMNWAVIGASLFVSNIGSEHFIGLAG 73

  Fly    70 AIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGER-----MGGL------ 123
            :...||.......|...|.|...|..|.......|..||.:.|...:|.:     ..||
Zfish    74 SGAASGFAVAAWEFNALLLLQLLGWVFIPVYIHSGVYTMPEYLSKRYGGKRLKIYFAGLSLLLYI 138

  Fly   124 ---LFLPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQ 185
               |.:....|.:|    |..:||..|.:        |:||...:....|:.|||.:|.|||.:|
Zfish   139 FTKLSVDLYAGALF----IQESLGWNLYL--------SIILLISMTALLTVTGGLVAVIYTDTLQ 191

  Fly   186 LFCIFIGL--------------------WM-CIP-----FAWSN---EHVGSLS----------- 210
            ...:..|.                    :| .:|     .|.||   |:..|..
Zfish   192 AVLMIGGALTLTIISLIKVGGLEGVREKYMEAVPNVTAILASSNFSFEYTNSCRIYPKPDSLKLL 256

  Fly   211 ----DLEVDWIGHV---EPKKHWLYIDYGLLLVFGGIPW---QVYFQRVLSSKTAGRAQLLSYVA 265
                |.::.|.|.:   .|...|.              |   ||..||||::|....|:..:.:|
Zfish   257 RGPLDEDIPWPGFLLGQTPSSIWY--------------WCADQVIVQRVLAAKNIAHAKGSTLMA 307

  Fly   266 AAGCILMAIPPVLIGAIAKATPWNETDYKGP-----------------YPLTVDETSMILPMVLQ 313
            ....||.....|:.|.|::....:|....||                 ||..|   ..::|:.|:
Zfish   308 GVLKILPMFIIVIPGMISRILFPDELACIGPEHCMAVCGSQAGCSNIAYPRLV---MSVMPVGLR 369

  Fly   314 YLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGI 378
            .|.        :..:.||:||..||...||:::|..::||:: |.:||..|::.:.|:.:|.
Zfish   370 GLM--------MAVMIAALMSDLDSIFNSASTIFTLDIYKML-RARASSRELVVIGRIFVIF--- 422

  Fly   379 LATIMALTIPSIYGLWSMCSDLVYVIL----------FPQLLMVVHFKKHCNTYGSLSAYIVALA 433
               ::|::|..:..:..|....:|:.:          ...|.::..|.|.||..|:....:....
Zfish   423 ---MVAISIAWVPVIIEMQGGQMYLYIQEVAGYLTPPIAALFLLGVFWKRCNEIGAFCGGMTGFV 484

  Fly   434 IRLSGGEAILGLAPLIKYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYD 498
            :    |...|.|..:.:.|..|:..:...|..|...|.:: ..|..:|....::......||..:
Zfish   485 L----GTTRLLLGFIYREPKCDQPDERPAFITRIHYMYIA-AGLFWISGLVAVVVSLCTTPPDEE 544

  Fly   499 YF------------RCVV--------------------NIPEDVQRV-----------------G 514
            ..            |.||                    ::|||||:.                 .
Zfish   545 RIKRTTMWGLRKLRRLVVTEREEMYKLTNGSGNGILKKDVPEDVQKEKCLDGADIKLLLPSPCDQ 609

  Fly   515 DPSESGEQLSVMAGPLARSYG---AATMAGKDERNGRINPALESDDD---------------LPV 561
            ||:....:.|.   |: ..||   |..:..|||.        :|||:               ..|
Zfish   610 DPTTPNTEAST---PM-ELYGNGHAKLVKQKDES--------QSDDESCLQVIDWICCHKEKTSV 662

  Fly   562 AEARRINQETAQAQVKKMLDNATGVK 587
            .|.:.|.::  :..:::||.....:|
Zfish   663 VEPKFIKED--EETIREMLHEPPKIK 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	121/564 (21%)
slc5a3b	XP_005167848.1	SLC5-6-like_sbd	12..709	CDD:444915	151/740 (20%)