Protein Alignment ChT and Slc5a3

DIOPT Version :9

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_059087.2
• Gene: Slc5a3 / 53881
• MGIID: 1858226
• Length: 718
• Species: Mus musculus
• Alignment Length: 721
• Identity: 154/721 - (21%)
• Similarity: 250/721 - (34%)
• Gaps: 256/721 - (35%)

  Fly     1 MINIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYIN 65
            ::..|.:..:.|:::|::.:|.:|..|  |...:.....|||||:           |||..|
Mouse     4 VLEAADIAVVALYFILVMCIGFFAMWK--SNRSTVSGYFLAGRSM-----------TWVAIG--- 52

  Fly    66 GTAEAIYTS--------GLVWCQAPFGYA----------LSLVFGGIFFANPMRKQGYITMLDPL 112
               .:::.|        ||....|..|:|          |..:.|.:|....:| .|..||.:.|
Mouse    53 ---ASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIR-SGVYTMPEYL 113

  Fly   113 QDSF-GERMGGLLFLPALCGEVFWAA-GILAALGATLSV-----------IIDMDHRTSVILSSC 164
            ...| |.|:           :|::|| .:|..:...|||           .:..:...||||...
Mouse   114 SKRFGGHRI-----------QVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIG 167

  Fly   165 IAIFYTLFGGLYSVAYTDVIQLFCIFIG------------------------------------- 192
            :....|:.|||.:|.|||.:|...:.||
Mouse   168 MTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYN 232

  Fly   193 -----LWMCIPFAWSNEHVGSLSDLEVDWIGHV---EPKKHWLYIDYGLLLVFGGIPW---QVYF 246
                 ..|..|.|.:.:.:...:|.:|.|.|.:   .|...|.              |   ||..
Mouse   233 LSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWY--------------WCADQVIV 283

  Fly   247 QRVLSSKTAGRAQLLSYVAAAGCILMA-----IPPVLI---GAIAKATPWNETDYKGPYPLTVDE 303
            ||||::|....|:        |..|||     :|..:|   |.|::.             :..||
Mouse   284 QRVLAAKNIAHAK--------GSTLMAGFLKLLPMFIIVVPGMISRI-------------VFADE 327

  Fly   304 TSMI-------------------LPMVLQYLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFAR 349
            .:.|                   .|.::..|.|..:....:..:.||:||..||...||:::|..
Mouse   328 IACINPEHCMQVCGSRAGCSNIAYPRLVMTLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTL 392

  Fly   350 NVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWSMCSDLVYVIL--------- 405
            :||||| |:.||..|::.|.|   |.|..:..|....:|.|.   .|....:|:.:
Mouse   393 DVYKLI-RKSASSRELMIVGR---IFVAFMVVISIAWVPIIV---EMQGGQMYLYIQEVADYLTP 450

  Fly   406 -FPQLLMVVHFKKHCNT----YGSLSAYIVALAIRLSGGEAILGL---APLI----KYPGYDEET 458
             ...|.::..|.|.||.    ||.::.:::. |:||     ||..   ||..    ..||:.::.
Mouse   451 PVAALFLLAIFWKRCNEQGAFYGGMAGFVLG-AVRL-----ILAFTYRAPECDQPDNRPGFIKDI 509

  Fly   459 KEQMFPFRTMAMLLSLVTLI--------------SVSWWTKMMFESGKLPPSYD---------YF 500
             ..|:....:..:..|:|:|              :.::|:|....:.:.....|         ..
Mouse   510 -HYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYKMQEKSIL 573

  Fly   501 RCVVNI--------------------PEDVQRVGDPSESGEQLSVMA-----GPL-ARSYGAATM 539
            :|..|.                    ||||..:....|.|..::.|.     .|: |.|.|.|.:
Mouse   574 QCSENSEVISHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAAL 638

  Fly   540 AGKDER 545
            .|:.||
Mouse   639 MGERER 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	133/614 (22%)
Slc5a3	NP_059087.2	SLC5sbd_SMIT	9..718	CDD:271382	153/716 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810