DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ChT and salt

DIOPT Version :9

Sequence 1:	NP_650743.1	Gene:	ChT / 42245	FlyBaseID:	FBgn0038641	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	620	Identity:	133/620 - (21%)
Similarity:	246/620 - (39%)	Gaps:	118/620 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VLFYLLILV---VGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIY 72
            ::|.|::..   :|::.|...::.|.:||.:....|...|.|.|..:::...|...::..||. |
  Fly    31 IVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAET-Y 94

  Fly    73 TSG-----LVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGE 132
            :.|     :||........|..:...:|:.|.:.     ...:.|:..|.:|...|:.:..:..:
  Fly    95 SFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVS-----NCYEYLELRFSKRTRQLVTITFILNQ 154

  Fly   133 VFWAAGILAALGATLSVIIDMD-HRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMC 196
            .......:.......|.:...: |..:.::|| |.:|||:.||:.:|.:|||:|...:.|.:.:.
  Fly   155 FLMLPVYMFVPSLAFSQVTGYNIHLINTVVSS-ICVFYTMLGGIKAVVWTDVVQGSVMLISVVLV 218

  Fly   197 IPFAWSNEHVGSLSDL--------EVDWIGHVEPKKHWLYID---YGLLLVFG--GIPWQVYFQR 248
            .....||  .|.::::        ..|:...::|:....:|.   .|||:..|  |:. |...||
  Fly   219 AILGTSN--TGGITNVLENAAEGGRFDFSFGIDPRLRLTFISGMASGLLMWTGKLGLD-QSCVQR 280

  Fly   249 VLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPL---TVDETSMILPM 310
            ::|..:.|.|:....:|..|.:|:.......|.|..|.      |.|..|:   .|.:...::|.
  Fly   281 IVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAY------YYGCDPIQAGLVSKPDKLMPF 339

  Fly   311 VLQYLTPDFVS-FFGLGAVSAAVMSSADSSVLSAA-SMFARNVYKLIFRQKA--SEMEIIWVMRV 371
            .:|    |.:. ..|:..|..:.:.||..|.|||: :.||..||....:.:.  ||.:....|::
  Fly   340 FIQ----DIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAKANATMKL 400

  Fly   372 AIIVVG------------------ILATIMALTIPSIYGLWSM------CSDLVYV--ILFPQLL 410
            .|:|:|                  .:.||..:.:.::.|::.:      |:..|.|  |.|..|:
  Fly   401 VIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLV 465

  Fly   411 MV-------VHFKKHCNTYGSL----------SAYIVALAIRLS-----GGEAILGL-APLIKYP 452
            |:       ::||.....|..|          ...::..|||..     |..||..| ||.....
  Fly   466 MLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTT 530

  Fly   453 GYDEETKEQMFP-----FRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYF-RCVVNIPEDVQ 511
            .:|......::.     ::.:..||.....|.:|:...:..|..:.|..|..| |.::|.|..|.
  Fly   531 AFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVL 595

  Fly   512 RVGDPSESGEQLSVMAGPLA------RSYGAATMA 540
            .:       |:|.:.. ||:      :..|:||.|
  Fly   596 EL-------EELPLKT-PLSEEQIKEKENGSATEA 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	116/552 (21%)
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	117/554 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448239
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740