Protein Alignment ChT and Slc5a12

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 134/668 - (20%)
• Similarity: 243/668 - (36%)
• Gaps: 151/668 - (22%)

  Fly    11 VLFYLLILV---VGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIY 72
            |:|..|.::   :|::...|::....| .|.::.||.:.......::||:::....:.||...:|
  Rat    12 VVFAALFVISSGIGVFFAIKERKKTTS-REFLVGGRQMSFAPVALSLTASFMSAVTVLGTPAEVY 75

  Fly    73 TSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGEVFWAA 137
            ..|..:......||..:.|....|.....:.|..:..:.||..|.:.:.....:..:...:.:..
  Rat    76 RFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQTILYTG 140

  Fly   138 GILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMCIPFAWS 202
            .::.|....|:.:...:...||..:..:..||...|||.:|.:||..|:..:.:| ::.:....|
  Rat   141 VVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVG-FLTVLIQGS 204

  Fly   203 NEHVGSLSD-LE----------VDWIGHVEP-KKHWLYIDYGLLLVFGGIPW-------QVYFQR 248
            | |||...: ||          ||:  .|:| ::|    .:..:.|.|...|       |...||
  Rat   205 N-HVGGFDNVLEQARNGSRLDIVDF--DVDPLRRH----TFWTIAVGGTFTWLGIYGVNQSTIQR 262

  Fly   249 VLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKA-----TPWNETDYKGPYPLTVDETSMIL 308
            .:|.||...|:|..|....|..::.:..|..|.|..|     .||.......|        ..::
  Rat   263 CISCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAP--------DQLM 319

  Fly   309 PMVLQYLTPDFVSFFGLGAVSAA-----VMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWV 368
            |..:..:   |.:..||..:..|     .:|:..:|:.:.|::...:..|..|...:..:. .|:
  Rat   320 PYFVMEI---FATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDTLS-TWI 380

  Fly   369 MRVAIIVVGILATIMALTIPSIYG--------LWSMCSD-----LVYVILFPQLLMVVHFKKHCN 420
            .:...::.||:.|.||: :.|:.|        :..||..     ....::||    .|::|
  Rat   381 SKGLCLLFGIICTSMAV-LASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFP----FVNWK---- 436

  Fly   421 TYGSLSAYIVALAIRLSGGEAILGLAPLIKYPGYDEETKE---------QMFPFRTMAMLLSLVT 476
              |:|...:..:.:..     .:|:...: ||..|.:|..         |.....|.|..||...
  Rat   437 --GALGGLLTGITLSF-----WVGIGAFV-YPAPDSKTLPLPLSTEFCVQQNKTTTEAYQLSSRP 493

  Fly   477 LISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAG 541
            :::.:|::.          ||.||..|                 ..|..:|..:..|:......|
  Rat   494 VLADTWYSL----------SYLYFSAV-----------------GCLGCIAAGIIISFLTGRQRG 531

  Fly   542 KDERNGRINPALESDDDLPVAE---------------ARRINQETAQAQVKKMLDNATGVKPSGG 591
            ||     ::|.|..    ||..               ..|.:|||.|    ..||:.:..|....
  Rat   532 KD-----VDPLLIR----PVCNLFCFWSKKYKTLCWCGVRHDQETEQ----DYLDSGSAWKQGVE 583

  Fly   592 GGGHLQSQSGMAMPTAEQ 609
            .|    .|:|:...|..|
  Rat   584 SG----LQNGLKQDTLSQ 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	105/523 (20%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	114/579 (20%)