Protein Alignment ChT and Slc5a11

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 138/564 - (24%)
• Similarity: 237/564 - (42%)
• Gaps: 129/564 - (22%)

  Fly     5 AGVVSIVLFYLLILVVGIWAG-RKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTA 68
            |.:|.:||::|.:|.||:|:. |.|:   |:.:...|||..:..:....::.|:.||.|:..|.|
  Rat    27 ADIVVLVLYFLFVLAVGLWSTVRTKR---DTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLA 88

  Fly    69 EAIYTSGLVWCQAPFGYALSLVFGGIFFA---NPMRKQGYI-TMLDPLQDSF-GERMGGLLFLPA 128
            .:....|:    :...|.|:.:|..:..|   .|:...|.: ||.:.|:..| |.|:...|.:..
  Rat    89 GSGAAVGI----SVAAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRRRFGGSRIPITLAVLY 149

  Fly   129 LCGEVFWAAGILAALGAT-LSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIG 192
            |...:|....:....||. :...:.:|...:::....:...||:.|||.:|.|||.:|...:.||
  Rat   150 LFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVIMLIG 214

  Fly   193 LWMCIPFAW------------------SNEHVGSLSDLEVDWIGHV--EPKKH---WLYIDYGLL 234
            .::.:.:::                  ||....|...|..:...|:  :|...   |..|.:|:
  Rat   215 AFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGILFGM- 278

  Fly   235 LVFGGIP----W---QVYFQRVLSSKTAGRAQ----LLSYVAAAGCILMAIPPVLIGAIAK---- 284
                .||    |   ||..||.|::|....|:    :.:|:......||..|    |.:::
  Rat   279 ----SIPSLWYWCTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVFP----GMVSRILFP 335

  Fly   285 ---------------ATPWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGAVSAAVMS 334
                           :.|...:|.  .||..|.|   :||..|:.|.        :..:.||:||
  Rat   336 DQVACAHPDICQRVCSNPSGCSDI--AYPKLVLE---LLPTGLRGLM--------MAVMVAALMS 387

  Fly   335 SADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWSMCSD 399
            |..|...||:::|..:::..| |.:|||.|::.|.||.::.   |..:..|.||.:..  |....
  Rat   388 SLTSIFNSASTIFTMDLWHHI-RPRASERELMIVGRVFVLA---LVLVSILWIPVVQA--SQGGQ 446

  Fly   400 L-VYV-----ILFPQLLMVV---HFKKHCNTYGSLSAYIVALAIRLSGGEAILGLAPLI-----K 450
            | :|:     .|.|.:.:|.   .|.|..|..|:.|..|:.|         :|||..||     .
  Rat   447 LFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFSGLILGL---------LLGLVRLILDFVYV 502

  Fly   451 YPGYDEE------TKEQMFPFRTMAMLLS---LVTLISVSWWTK 485
            .|..|:.      .|:..:.:  .:|:||   |:|:.:|||:|:
  Rat   503 QPRCDQPDDRPAVVKDVHYLY--FSMILSSTTLITVFTVSWFTE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	133/556 (24%)
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:444915	137/563 (24%)