Protein Alignment ChT and Slc5a1

DIOPT Version :9

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Alignment Length: 679
• Identity: 151/679 - (22%)
• Similarity: 270/679 - (39%)
• Gaps: 147/679 - (21%)

  Fly     3 NIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYI--- 64
            |.|.:..||:::::::.||:||......|  :.....|||||:..:....::.|:.:|.|:.
Mouse    25 NAADISVIVIYFVVVMAVGLWAMFSTNRG--TVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87

  Fly    65 --NGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMR-KQGYITMLDPLQDSFGER------- 119
              .|.|..|...|..|    ....|.:|.|.||.  |:. |.|.:||.:.|:..||.:
Mouse    88 AGTGAAAGIAMGGFEW----NALVLVVVLGWIFV--PIYIKAGVVTMPEYLRKRFGGKRIQIYLS 146

  Fly   120 -MGGLLFL-PALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTD 182
             :..||:: ..:..::|..|       ..:::.:.:|...::.:...|...||:.|||.:|.|||
Mouse   147 VLSLLLYIFTKISADIFSGA-------IFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTD 204

  Fly   183 VIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIGHVEPK--------KHWLYI----DYGLLL 235
            .:|...:.:|.::...||: || ||........::..:..|        |...|.    .:.:..
Mouse   205 TLQTAIMLVGSFILTGFAF-NE-VGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSFHIFR 267

  Fly   236 --VFGGIPW------------------QVYFQRVLSSKTAGRAQ----LLSYVAAAGCILMAIPP 276
              :.|.:||                  ||..||.||:|.....:    |..|:......||.:|.
Mouse   268 DPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPG 332

  Fly   277 VL-----IGAIAKATPWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGAVSAAVMSSA 336
            ::     ...||...|.....|.|   ..|..|::..|.::..|.|:.:....|..:.|::|||.
Mouse   333 MISRILYTEKIACVLPEECQKYCG---TPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSL 394

  Fly   337 DSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWS-MCSDL 400
            .|...||:::|..::|..| |:||||.|::...|:.|:|   |..|....:|.:....| ...|.
Mouse   395 TSIFNSASTLFTMDIYTKI-RKKASEKELMIAGRLFILV---LIGISIAWVPIVQSAQSGQLFDY 455

  Fly   401 VYVI---LFPQL---LMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAILGLAPLIKYPGYDEETK 459
            :..|   |.|.:   .::..|.|..|..|:....|:..         ::|::.:|....|.  |.
Mouse   456 IQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGF---------LIGISRMITEFAYG--TG 509

  Fly   460 EQMFP--------------FRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRC-------- 502
            ..|.|              |..:..::|::|::.:|:.||      .:|..:.|..|
Mouse   510 SCMEPSNCPKIICGVHYLYFAIILFVISVITILIISFLTK------PIPDVHLYRLCWSLRNSKE 568

  Fly   503 ---------VVNIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAGKDERNGRINPALESDDD 558
                     ..:||||.:...:......|..  .|...|:|.  ...|.|:..|   |.:..:::
Mouse   569 ERIDLDAGEEEDIPEDSKDTIEIDTEAPQKK--KGCFRRAYD--LFCGLDQDKG---PKMTKEEE 626

  Fly   559 LPVAEARRINQ-ETAQAQVKKMLDNATGV 586
                ||.::.. :|::..:.:.:.|..|:
Mouse   627 ----EAMKMKMTDTSEKPLWRTVVNINGI 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	126/550 (23%)
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:294310	150/677 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810