Protein Alignment ChT and SLC5A10

DIOPT Version :9

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 130/628 - (20%)
• Similarity: 237/628 - (37%)
• Gaps: 185/628 - (29%)

  Fly     2 INIAGVVSIVLFYLLILVVGIW----AGRKKQSGNDSEEEVMLAGRSI----------------G 46
            :::|.::.|.:::.|.:.||||    |.|...:|      ..||||.:                |
Human    16 LSVADIIVITVYFALNVAVGIWSSCRASRNTVNG------YFLAGRDMTWWPIGASLFASSEGSG 74

  Fly    47 LFVGIFTMTATWVGGGYINGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDP 111
            ||:|:       .|.|...|.|.|    |..|.......||:.||..|:.::.:     :|:.:.
Human    75 LFIGL-------AGSGAAGGLAVA----GFEWNATYVLLALAWVFVPIYISSEI-----VTLPEY 123

  Fly   112 LQDSF-GERMGGLLFLPALCGEVFWAAGILAALGAT-LSVIIDMDHRTSVILSSCIAIFYTLFGG 174
            :|..: |:|:...|.:.:|...||....:....||. :.:.:..:...|.||:..|...||:.||
Human   124 IQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGG 188

  Fly   175 LYSVAYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIG--------------------H 219
            |.:|.|||.:|...:.:|..:....|:  :.:|....||..:..                    |
Human   189 LAAVIYTDALQTLIMVVGAVILTIKAF--DQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMH 251

  Fly   220 VEPKKH-----WLYIDYGLLLVFGGIPW-----QVYFQRVLSSKTAGRAQLLSYVAAAGCILMAI 274
            :....|     |..:.:||.::   ..|     ||..||.||::....|:..|.:|:   .|..:
Human   252 MFRDPHTGDLPWTGMTFGLTIM---ATWYWCTDQVIVQRSLSARDLNHAKAGSILAS---YLKML 310

  Fly   275 PPVLI---GAIAKATPWNETDYKGPYPLTVDET----------------------SMILPMVLQY 314
            |..||   |.|::|.......|:..:.::|..|                      ::..|.::..
Human   311 PMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375

  Fly   315 LTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAI------ 373
            |.|..:....:..:.||:|||..|...|::::|..::::.: |.::.|.|::.|.|..|
Human   376 LMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRL-RPRSGERELLLVGRTGIPSTPPA 439

  Fly   374 -----------------IVVGILATIMALTIPSIYGL---W-----------------SMCSDLV 401
                             .::|::...:.|.|.::.|:   |                 |:.|.|.
Human   440 PQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLA 504

  Fly   402 YVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAI----LGLAPLIKYPGYDEETKEQM 462
            ..:....:|.|  |.:..|..|:....|..|.:   |...:    |..||    |..:.:|:..:
Human   505 PPVTAVFVLGV--FWRRANEQGAFWGLIAGLVV---GATRLVLEFLNPAP----PCGEPDTRPAV 560

  Fly   463 ---FPFRTMAMLL-----------SLVT-------LISVSWWT 484
               ..:...|:.|           ||:|       :.:::|||
Human   561 LGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWT 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	126/618 (20%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	130/627 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146507
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740