Protein Alignment ChT and Slc5a5

DIOPT Version :9

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_444478.2
• Gene: Slc5a5 / 114479
• MGIID: 2149330
• Length: 618
• Species: Mus musculus
• Alignment Length: 649
• Identity: 133/649 - (20%)
• Similarity: 236/649 - (36%)
• Gaps: 173/649 - (26%)

  Fly    12 LFYLLILV---VGIWAGRKKQSGNDSEEEVMLAGRSIGLF-VGIFTMTATWVGGGYINGTAEAIY 72
            :|..::||   :|:|.|..: .|..|.::....||.:... ||: ::.|:::....:.|......
Mouse    19 VFATMLLVSTGIGLWVGLAR-GGQRSADDFFTGGRQLAAVPVGL-SLAASFMSAVQVLGVPAEAA 81

  Fly    73 TSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERM---GGLLFLPA---LCG 131
            ..||.:.....|..|:.:...:.|.....:.|..:....|:..|...:   |.|.:|.|   ..|
Mouse    82 RYGLKFLWMCVGQLLNSLLTALLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTG 146

  Fly   132 EVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLW-- 194
            .|.:|..::      |:.:..:|...|::.:..|...||..||:.:|.:|||.|:..:.:|.|
Mouse   147 IVIYAPALI------LNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVI 205

  Fly   195 -----MCIPFAWS------NEHVGSLSDLEVDWIGHVEPKKHWLYIDYGLLLVFGGIPW------ 242
                 |.:...|:      |....:|.|.:.|      |:..:.:..:   :|.|.:.|
Mouse   206 LARGVMLMGGPWNVLSLAQNHSRINLMDFDPD------PRSRYTFWTF---VVGGSLVWLSMYGV 261

  Fly   243 -QVYFQRVLSSKTAGRAQ---------LLSYVAAAGC--ILMAI-----PPVLIGAIAKATPWNE 290
             |...||.::..|..:|:         |...||:|.|  |:|.:     .|:|.|.||....:
Mouse   262 NQAQVQRYVACHTERKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRIAAPDQY-- 324

  Fly   291 TDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVY--- 352
                  .||.|.:....||.|     |...    |....:..:|:|.:|:.:.|::...::.
Mouse   325 ------MPLLVLDIFEDLPGV-----PGLF----LACAYSGTLSTASTSINAMAAVTVEDLIKPR 374

  Fly   353 -------KLIFRQKASEMEIIW---VMRVA----IIVVGILA---TIMALTIPSIYGLWSMCSDL 400
                   ||:|..|.  :..|:   .:.||    ::..|:|.   |:|.:....:.|.:::
Mouse   375 MPSLAPRKLVFISKG--LSFIYGSTCLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTL---- 433

  Fly   401 VYVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRL---------SGGEAILGLAP--------- 447
              .:|.|.          |||.|.||.....||:.|         ..||..:|:.|
Mouse   434 --GMLLPA----------CNTPGVLSGLTAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNA 486

  Fly   448 --LIKYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDV 510
              |...||....::.  .|...|                    :||: |...|.|..|..:....
Mouse   487 SVLPSPPGAANTSRG--IPSSGM--------------------DSGR-PAFADTFYAVSYLYYGA 528

  Fly   511 QRVGDPSESGEQLSVMAGPLARS------------YGAATMAGKDERNGRINPALESDDDLPVA 562
            .........|..:|.:.||..||            ...|::|.|::.....:..::..:|:|.|
Mouse   529 LGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTTTLEDSLVKGPEDIPAA 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	115/554 (21%)
Slc5a5	NP_444478.2	SLC5sbd_NIS	15..549	CDD:271393	125/604 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	571..618		4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836571
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830