Protein Alignment ChT and slc5a3a

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001153309.1
• Gene: slc5a3a / 100004287
• ZFINID: ZDB-GENE-090312-3
• Length: 671
• Species: Danio rerio
• Alignment Length: 689
• Identity: 153/689 - (22%)
• Similarity: 250/689 - (36%)
• Gaps: 200/689 - (29%)

  Fly     5 AGVVSIVLFYLLILVVG---IW-AGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYIN 65
            |.::.:.::::|:|..|   :| |.|...||      ..|||||:..||...::..:.:|..:..
Zfish     8 ADIIVVAMYFVLVLCFGFFSMWRANRGTVSG------YFLAGRSMNWFVIGASLFVSNIGSEHFI 66

  Fly    66 GTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLF----- 125
            |.|.:...|||......|...|.|...|..|.......|..||.:.|...||.....:.|
Zfish    67 GLAGSGAASGLAVGAWEFNAILLLQLLGWVFIPVYIHSGVYTMPEYLSKRFGGNRLKIYFASLTL 131

  Fly   126 ---------LPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYT 181
                     :....|.:|    |..:||..|.:        |:||...:....|:.|||.:|.||
Zfish   132 LLYIFTKLSVDLYSGALF----IQESLGWNLYL--------SIILLITLTALLTVTGGLVAVIYT 184

  Fly   182 DVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIG--------------------HVEPKKHW 226
            |.:|.|.:..|. :|: .|.|...||.|..|...::.                    ||.||..
Zfish   185 DTLQAFLMISGA-LCL-MAISLVKVGGLEGLRTKYMNALPNITFITLENNLTYSNSCHVNPKAD- 246

  Fly   227 LYIDYGLLL--VFGGIPW------------------QVYFQRVLSSKTAGRAQLLSYVAAAGCIL 271
               .:.||.  :...:||                  ||..||||:::....|:..:.:|.   :|
Zfish   247 ---SFKLLRSPLDKDLPWPAFLLGQTPASIWYWCADQVIVQRVLAARNIAHAKGSTLLAG---VL 305

  Fly   272 MAIPPVLI---GAIAKATPWNETDYKGP-----------------YPLTVDETSMILPMVLQYLT 316
            ..:|..:|   |.|::....:|....||                 ||..|   ..|:|:.|:.|.
Zfish   306 KVLPMFIIVIPGMISRVLFADELACIGPEHCMQVCNSRAGCTNTAYPRLV---MNIMPVGLRGLM 367

  Fly   317 PDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILAT 381
                    :..:.||:||..||...||:::|..::||:| |.:||..|::.|.|:.:::
Zfish   368 --------MAVMLAALMSDLDSIFNSASTIFTLDIYKMI-RHQASSKELMVVGRLFVVL------ 417

  Fly   382 IMALTIPSIYGLWSMCSDLVYVIL----------FPQLLMVVHFKKHCNTYGSLSAYIVALAIRL 436
            |:|::|..:..:..|....:::.:          ...|.::....|.||..|:.....|.|
Zfish   418 IVAISIAWVPFVIEMQGGQMFLYIQEVSDYLTPPIAALFLLGVLWKRCNETGAFWGGFVGL---- 478

  Fly   437 SGGEAILGLAPLI-----KYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPS 496
                 |||:..||     :.|..|.......| .:.:..:.....|..||.:..::......||
Zfish   479 -----ILGIVRLILAFVYREPDCDSVDDRPAF-IKDVHFMYVAAVLFWVSGFVMVVVSLCTNPP- 536

  Fly   497 YDYFRCVVNIPEDVQRVGDPSESGEQLS--VMAGPLARSYGAATMAGKDERNGRINPALESDDDL 559
                                  |.||:|  .:.|...|:..|.|.|  ...||::...|:..:..
Zfish   537 ----------------------SKEQISKTTLWGLRNRNQPADTKA--KGGNGKLEQTLDGVEFQ 577

  Fly   560 PVAEARRINQETAQAQVKKMLDNATGVKPSGGGGGHLQS 598
            |:.              .:||.|           |||::
Zfish   578 PLP--------------PEMLPN-----------GHLEA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	129/566 (23%)
slc5a3a	NP_001153309.1	SLC5-6-like_sbd	9..671	CDD:444915	152/688 (22%)