Protein Alignment CG7702 and TPBG

DIOPT Version :9

• Sequence 1: NP_650740.1
• Gene: CG7702 / 42242
• FlyBaseID: FBgn0038638
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001159864.1
• Gene: TPBG / 7162
• HGNCID: 12004
• Length: 420
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 109/447 - (24%)
• Similarity: 180/447 - (40%)
• Gaps: 115/447 - (25%)

  Fly    66 ILARWPEQFGSQAIASGAASE--IVVSYSGNRIKLLQQLPA----TNASLTLSCRHCGLQDLQAP 124
            :|..|.......:.||..:|.  .:.|....:..|..|.||    :.|:.|:.|.:..|.::..
Human    24 VLLGWVSSSSPTSSASSFSSSAPFLASAVSAQPPLPDQCPALCECSEAARTVKCVNRNLTEVPT- 87

  Fly   125 LFMDVP-NVQALYISWNDITDDALVPDLFRGPFRNTRYEPIG-LRDLDLSHNRIVRLDRRLFEHT 187
               |:| .|:.|:::.|.:   |::|   .|.|  .|..|:. |..|:||.:|:..:....|||.
Human    88 ---DLPAYVRNLFLTGNQL---AVLP---AGAF--ARRPPLAELAALNLSGSRLDEVRAGAFEHL 141

  Fly   188 PHLTKLNLAYNKLSSLD----EATTASIGSVATLQRLDLSHNGLMTLPAQLFSKLTSLRFLDVSG 248
            |.|.:|:|::|.|:.|.    ..:.||:.:.:.|..|.|:|    .:|.:           |...
Human   142 PSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILNH----IVPPE-----------DERQ 191

  Fly   249 N-EFSTMPASLQLLGKSLV---QLNLAGNAFLSLKENSLQGLVSLKRLNISSMPSLRSLEKGALN 309
            | .|..|..:..|.|::|.   :|.||.|.||.|..:.|                        ..
Human   192 NRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVL------------------------AQ 232

  Fly   310 LPALEHLDCSRNSKLERLELADLLSSRNLSQLD---LSWNALTTLVINATGSSNNSSNSTNETWP 371
            ||:|.|||.|.||    |.....:|.|||:.|:   |..|||..|        :|.:.:..:..|
Human   233 LPSLRHLDLSNNS----LVSLTYVSFRNLTHLESLHLEDNALKVL--------HNGTLAELQGLP 285

  Fly   372 RLRRMSISGNPWYCSCEL------FKALELI-GLNHIDREWDGTEARCETPYLLAGSPLSNL-TA 428
            .: |:.:..|||.|.|.:      .|..|:: |.:.:         .|..|..:....|..| :|
Human   286 HI-RVFLDNNPWVCDCHMADMVTWLKETEVVQGKDRL---------TCAYPEKMRNRVLLELNSA 340

  Fly   429 ERICKMVIPKKYREVDEEPPRFLRRHYIILTAIIASIVLVIGLVIGFVVVCVRRRLK 485
            :..|..::|..           |:..|:.|..::|    :||.:...|:...|:.:|
Human   341 DLDCDPILPPS-----------LQTSYVFLGIVLA----LIGAIFLLVLYLNRKGIK 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7702	NP_650740.1	leucine-rich repeat	110..131	CDD:275380	5/21 (24%)
		LRR_RI	<123..267	CDD:238064	40/153 (26%)
		leucine-rich repeat	132..165	CDD:275380	9/32 (28%)
		LRR_8	165..227	CDD:290566	21/66 (32%)
		leucine-rich repeat	166..189	CDD:275380	8/22 (36%)
		leucine-rich repeat	190..213	CDD:275380	8/26 (31%)
		LRR_8	216..273	CDD:290566	15/60 (25%)
		leucine-rich repeat	217..240	CDD:275380	5/22 (23%)
		leucine-rich repeat	241..264	CDD:275380	6/23 (26%)
		LRR_8	263..321	CDD:290566	16/60 (27%)
		leucine-rich repeat	265..288	CDD:275380	9/25 (36%)
		leucine-rich repeat	289..312	CDD:275380	1/22 (5%)
		leucine-rich repeat	313..337	CDD:275380	9/23 (39%)
TPBG	NP_001159864.1	LRRNT	61..95	CDD:214470	10/37 (27%)
		leucine-rich repeat	73..95	CDD:275380	6/25 (24%)
		LRR 1. /evidence=ECO:0000269|PubMed:24582434	92..113		7/28 (25%)
		LRR_8	93..154	CDD:338972	22/68 (32%)
		leucine-rich repeat	96..119	CDD:275380	8/30 (27%)
		LRR 2. /evidence=ECO:0000269|PubMed:24582434	116..139		6/22 (27%)
		leucine-rich repeat	120..143	CDD:275380	8/22 (36%)
		LRR 3. /evidence=ECO:0000269|PubMed:24582434	141..163		7/21 (33%)
		leucine-rich repeat	144..167	CDD:275380	6/22 (27%)
		LRR 4. /evidence=ECO:0000269|PubMed:24582434	172..204		9/46 (20%)
		leucine-rich repeat	175..211	CDD:275380	12/50 (24%)
		LRR 5. /evidence=ECO:0000269|PubMed:24582434	209..232		9/46 (20%)
		LRR_8	211..270	CDD:338972	25/86 (29%)
		leucine-rich repeat	212..235	CDD:275380	9/46 (20%)
		LRR 6. /evidence=ECO:0000269|PubMed:24582434	233..255		11/25 (44%)
		leucine-rich repeat	236..259	CDD:275380	12/26 (46%)
		LRR 7. /evidence=ECO:0000269|PubMed:24582434	256..275		8/26 (31%)
		leucine-rich repeat	260..283	CDD:275380	7/30 (23%)
		LRRCT	294..345	CDD:214507	13/59 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143368
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24364
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030