Protein Alignment CG7702 and Lrrn2

DIOPT Version :10

• Sequence 1: NP_650740.1
• Gene: CG7702 / 42242
• FlyBaseID: FBgn0038638
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001170839.1
• Gene: Lrrn2 / 289020
• RGDID: 1305482
• Length: 750
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 125/498 - (25%)
• Similarity: 198/498 - (39%)
• Gaps: 132/498 - (26%)

  Fly    13 AALLLATEVRSQHEDIPYQPVSNIC-QTCLC----LSTQDVDHRTHFNLDCSVRNFEHILARWPE 72
            |||||:. ..|.:..:|..|....| ..|.|    ..|....:|....:||:    :..|...|
  Rat     6 AALLLSW-AASTNTAVPVVPWRVPCPPQCACQIRPWYTPRSSYREATTVDCN----DLFLTAVP- 64

  Fly    73 QFGSQAIASGAASEIVVSYSGNRIKL--------LQQLPATNASLTLSCRHCGLQDLQAPLFMDV 129
                ..:.:|..:.::.|.|.:||:.        |.:|..:..|.: ..|.|   |.||     :
  Rat    65 ----PGLPAGTQTLLLQSNSISRIEQTELGYLANLTELDLSQNSFS-DARDC---DFQA-----L 116

  Fly   130 PNVQALYISWNDITDDALVPDLFRGPFRNTRYEPIGLRDLDLSHNRIVRLDRRLFEHTPHLTKLN 194
            |.:.:|::..|.::  .|....|.|..|        |::|.|:||::.|:..|.||...:|.:|:
  Rat   117 PQLLSLHLEENQLS--RLEDHSFAGLTR--------LQELYLNHNQLCRISPRAFEGLGNLLRLH 171

  Fly   195 LAYNKLSSLD--------EATTASIGS-------------VATLQRLDLSHNGLMTLPAQLFSKL 238
            |..|.|.::|        ......||.             :|.|:.|.|:...|..:.......|
  Rat   172 LNSNLLRTIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMSLREISDYALEGL 236

  Fly   239 TSLRFLDVSGNEFSTMPASLQLLGKSLVQLNLAGNAFLSLKENSLQ--------GLVSLKRLNIS 295
            .||..|....|:.:.:|.      ::|.|  :.|..||.|.:|.||        .::.||.|.::
  Rat   237 QSLESLSFYDNQLAQVPK------RALEQ--VPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLN 293

  Fly   296 SMPSLRSLEKGAL-NLPALEHLDCSRNSKLERLELADLLSSRNLSQLDLSWNALTTLVINATGSS 359
            :|..|.|::|.|| |||.|..||.:.|   .||......:..:|.|::       ||::|
  Rat   294 NMEELVSIDKFALVNLPELTKLDITNN---PRLSFIHPRAFHHLPQME-------TLMLN----- 343

  Fly   360 NNSSNS----TNETWPRLRRMSISGNPWYCSCELFKALELIGLNHIDREW---DGTEARCETPYL 417
            ||:.::    |.|:.|.|:.:.:.|||..|.|.:              .|   .||..|    ::
  Rat   344 NNALSALHQQTVESLPNLQEVGLHGNPIRCDCVI--------------RWANATGTHVR----FI 390

  Fly   418 LAGSPLSNLTAERICKMVIPK--KYREVDEEPPRFLRRHYIIL 458
               .|.|.|.||       |.  :.|.|.|.|.|.:..|.:.|
  Rat   391 ---EPQSTLCAE-------PPDLQRRPVREVPFREMTDHCLPL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7702	NP_650740.1	leucine-rich repeat	110..131	CDD:275380	5/20 (25%)
		leucine-rich repeat	132..165	CDD:275380	6/32 (19%)
		LRR	<165..>382	CDD:443914	67/250 (27%)
		leucine-rich repeat	166..189	CDD:275380	9/22 (41%)
		leucine-rich repeat	190..213	CDD:275380	7/30 (23%)
		leucine-rich repeat	217..240	CDD:275380	5/22 (23%)
		leucine-rich repeat	241..264	CDD:275380	4/22 (18%)
		leucine-rich repeat	265..288	CDD:275380	9/30 (30%)
		leucine-rich repeat	289..312	CDD:275380	11/23 (48%)
		leucine-rich repeat	313..337	CDD:275380	6/23 (26%)
Lrrn2	NP_001170839.1	LRRNT	28..72	CDD:214470	10/52 (19%)
		leucine-rich repeat	51..69	CDD:275380	4/26 (15%)
		leucine-rich repeat	71..94	CDD:275380	4/22 (18%)
		LRR	<85..>324	CDD:443914	69/268 (26%)
		leucine-rich repeat	95..118	CDD:275380	8/31 (26%)
		leucine-rich repeat	119..142	CDD:275380	5/24 (21%)
		leucine-rich repeat	143..166	CDD:275380	9/22 (41%)
		leucine-rich repeat	167..190	CDD:275380	6/22 (27%)
		leucine-rich repeat	191..214	CDD:275380	2/22 (9%)
		leucine-rich repeat	215..238	CDD:275380	5/22 (23%)
		leucine-rich repeat	239..262	CDD:275380	6/30 (20%)
		leucine-rich repeat	263..286	CDD:275380	6/22 (27%)
		leucine-rich repeat	287..311	CDD:275380	11/23 (48%)
		LRR_8	310..371	CDD:404697	20/75 (27%)
		leucine-rich repeat	312..334	CDD:275380	6/24 (25%)
		leucine-rich repeat	337..360	CDD:275378	7/34 (21%)
		PCC	342..>420	CDD:188093	27/110 (25%)
		leucine-rich repeat	361..373	CDD:275378	4/11 (36%)
		Ig	430..514	CDD:472250
		Ig strand B	441..445	CDD:409353
		Ig strand C	454..458	CDD:409353
		Ig strand E	480..484	CDD:409353
		Ig strand F	494..499	CDD:409353
		Ig strand G	507..510	CDD:409353