DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7702 and Tpbg

DIOPT Version :9

Sequence 1:NP_650740.1 Gene:CG7702 / 42242 FlyBaseID:FBgn0038638 Length:537 Species:Drosophila melanogaster
Sequence 2:NP_001158264.1 Gene:Tpbg / 21983 MGIID:1341264 Length:426 Species:Mus musculus


Alignment Length:461 Identity:108/461 - (23%)
Similarity:175/461 - (37%) Gaps:137/461 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 ILARWPEQFGSQAIASGAASEIVVSYSGNRIKLL----------QQLPA----TNASLTLSCRHC 116
            :|..|        :::.|.|..|.|.|.:....|          ::.||    :.|:.|:.|.:.
Mouse    24 VLLGW--------VSASAPSSSVPSSSTSPAAFLASGSAQPPPAERCPAACECSEAARTVKCVNR 80

  Fly   117 GLQDLQAPLFMDVPNVQALYISWNDITDDALVPDLFRGPFRNTRYEPIG-LRDLDLSHNRIVRLD 180
            .|.::.|.|   .|.|:.|:::.|.:|   ::|   .|.|  .|..|:. |..|:||.|.:..:.
Mouse    81 NLLEVPADL---PPYVRNLFLTGNQMT---VLP---AGAF--ARQPPLADLEALNLSGNHLKEVC 134

  Fly   181 RRLFEHTPHLTKLNLAYNKLSSLD----EATTASIGSVATLQRLDLSH-------------NGLM 228
            ...|||.|.|.:|:|::|.|::|.    ..:.||:.:.:.|:.|.|:|             .|::
Mouse   135 AGAFEHLPGLRRLDLSHNPLTNLSAFAFAGSNASVSAPSPLEELILNHIVPPEDQRQNGSFEGMV 199

  Fly   229 TLPAQLFSKLTSLRFLDVSGNEFSTMPASLQLLGKSLVQLNLAGNAFLSLKENSLQGLVSLKRLN 293
            .....:.:.|.|                .|.|.|  |.:|.||.|.||.|..:.|          
Mouse   200 AFEGMVAAALRS----------------GLALRG--LTRLELASNHFLFLPRDLL---------- 236

  Fly   294 ISSMPSLRSLEKGALNLPALEHLDCSRNSKLERLELADLLSSRNLSQLDLSWNALTTLVINATGS 358
                          ..||:|.:||. ||:.|..|..|...:..:|..|.|..|||..|       
Mouse   237 --------------AQLPSLRYLDL-RNNSLVSLTYASFRNLTHLESLHLEDNALKVL------- 279

  Fly   359 SNNSSNSTNETWPRLRRMSI--SGNPWYCSCEL------FKALELIGLNHIDREWDGTEARCETP 415
                .|||...|..|..:.:  ..|||.|.|.:      .|..|::.        |.....|..|
Mouse   280 ----HNSTLAEWHGLAHVKVFLDNNPWVCDCYMADMVAWLKETEVVP--------DKARLTCAFP 332

  Fly   416 YLLAGSPLSNLTAERI-CKMVIPKKYREVDEEPPRFLRRHYIILTAIIASIVLVIGLVIGFVVVC 479
            ..:....|.:|.:..: |..|:|:.           |:..|:.|..::|    :||.:...|:..
Mouse   333 EKMRNRGLLDLNSSDLDCDAVLPQS-----------LQTSYVFLGIVLA----LIGAIFLLVLYL 382

  Fly   480 VRRRLK 485
            .|:.:|
Mouse   383 NRKGIK 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7702NP_650740.1 leucine-rich repeat 110..131 CDD:275380 5/20 (25%)
LRR_RI <123..267 CDD:238064 40/161 (25%)
leucine-rich repeat 132..165 CDD:275380 9/32 (28%)
LRR_8 165..227 CDD:290566 21/79 (27%)
leucine-rich repeat 166..189 CDD:275380 8/22 (36%)
leucine-rich repeat 190..213 CDD:275380 8/26 (31%)
LRR_8 216..273 CDD:290566 14/69 (20%)
leucine-rich repeat 217..240 CDD:275380 6/35 (17%)
leucine-rich repeat 241..264 CDD:275380 3/22 (14%)
LRR_8 263..321 CDD:290566 14/57 (25%)
leucine-rich repeat 265..288 CDD:275380 9/22 (41%)
leucine-rich repeat 289..312 CDD:275380 1/22 (5%)
leucine-rich repeat 313..337 CDD:275380 8/23 (35%)
TpbgNP_001158264.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 33..53 6/19 (32%)
LRRNT 62..95 CDD:214470 10/35 (29%)
leucine-rich repeat 73..95 CDD:275380 7/24 (29%)
LRR 1 92..113 7/28 (25%)
LRR_8 93..154 CDD:338972 22/68 (32%)
leucine-rich repeat 96..119 CDD:275380 8/30 (27%)
LRR 2 116..139 6/22 (27%)
leucine-rich repeat 120..143 CDD:275380 8/22 (36%)
LRR 3 141..163 7/21 (33%)
leucine-rich repeat 144..167 CDD:275380 6/22 (27%)
LRR 4 172..210 5/37 (14%)
leucine-rich repeat 175..217 CDD:275380 9/57 (16%)
LRR 5 215..238 11/48 (23%)
LRR_8 217..276 CDD:338972 24/85 (28%)
leucine-rich repeat 218..241 CDD:275380 10/46 (22%)
LRR 6 239..261 10/22 (45%)
leucine-rich repeat 242..265 CDD:275380 8/23 (35%)
LRR 7 262..281 7/29 (24%)
leucine-rich repeat 266..289 CDD:275380 11/33 (33%)
LRRCT 300..351 CDD:214507 12/58 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833536
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24364
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.030

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