Protein Alignment CG7702 and Lrrn2

DIOPT Version :10

• Sequence 1: NP_650740.1
• Gene: CG7702 / 42242
• FlyBaseID: FBgn0038638
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_034862.1
• Gene: Lrrn2 / 16980
• MGIID: 106037
• Length: 730
• Species: Mus musculus
• Alignment Length: 417
• Identity: 105/417 - (25%)
• Similarity: 164/417 - (39%)
• Gaps: 118/417 - (28%)

  Fly   101 QLPATNASLTLSCRHCGLQDLQAPLFMDVPNVQALYISWNDITDDALVPDLFRGPFRNTRYEPI- 164
            :|||...:|.|........|.....::  .|:..|.:|.|..:|           .|:..::.:
Mouse    66 RLPAGTQTLLLQSNSISRIDQTELAYL--ANLTELDLSQNSFSD-----------ARDCDFQALP 117

  Fly   165 GLRDLDLSHNRIVRLDRRLFEHTPHLTKLNLAYNKLSSLDEATTASIGSVATLQRLDLSHNGLMT 229
            .|..|.|..||:.||:...|.....|.:|.|.:|:|..:.....|.:|:   |.||.|:.|.|.|
Mouse   118 QLLSLHLEENRLNRLEDHSFAGLTSLQELYLNHNQLCRISPRAFAGLGN---LLRLHLNSNLLRT 179

  Fly   230 LPAQLFSKLTSLRFLDVSGNEFSTM------P----ASLQLLGKSLVQLN--------------- 269
            :.::.|..|.:|..|.:.||:...:      |    .||.|.|.||.:::
Mouse   180 IDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMSLREISDYALEGLQSLESLSF 244

  Fly   270 ---------------LAGNAFLSLKENSLQ--------GLVSLKRLNISSMPSLRSLEKGAL-NL 310
                           :.|..||.|.:|.||        .::.||.|.:::|..|.|::|.|| ||
Mouse   245 YDNQLAQVPKRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNL 309

  Fly   311 PALEHLDCSRNSKLERLELADLLSSRNLSQLDLSWNALTTLVINATGSSNNSSNS----TNETWP 371
            |.|..||.:.|   .||......:..:|.|::       ||::|     ||:.::    |.|:.|
Mouse   310 PELTKLDITNN---PRLSFIHPRAFHHLPQME-------TLMLN-----NNALSALHQQTVESLP 359

  Fly   372 RLRRMSISGNPWYCSCELFKALELIGLNHIDREW---DGTEARCETPYLLAGSPLSNLTAERICK 433
            .|:.:.:.|||..|.|.:              .|   .||..|    ::   .|.|.|.||
Mouse   360 NLQEVGLHGNPIRCDCVI--------------RWANATGTHVR----FI---EPQSTLCAE---- 399

  Fly   434 MVIPK--KYREVDEEPPRFLRRHYIIL 458
               |.  :.|.|.|.|.|.:..|.:.|
Mouse   400 ---PPDLQRRPVREVPFREMTDHCLPL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7702	NP_650740.1	leucine-rich repeat	110..131	CDD:275380	2/20 (10%)
		leucine-rich repeat	132..165	CDD:275380	5/33 (15%)
		LRR	<165..>382	CDD:443914	72/269 (27%)
		leucine-rich repeat	166..189	CDD:275380	8/22 (36%)
		leucine-rich repeat	190..213	CDD:275380	6/22 (27%)
		leucine-rich repeat	217..240	CDD:275380	9/22 (41%)
		leucine-rich repeat	241..264	CDD:275380	9/32 (28%)
		leucine-rich repeat	265..288	CDD:275380	8/60 (13%)
		leucine-rich repeat	289..312	CDD:275380	11/23 (48%)
		leucine-rich repeat	313..337	CDD:275380	6/23 (26%)
Lrrn2	NP_034862.1	LRRNT	28..72	CDD:214470	3/5 (60%)
		leucine-rich repeat	51..69	CDD:275380	1/2 (50%)
		leucine-rich repeat	71..94	CDD:275380	3/24 (13%)
		LRR	<85..>324	CDD:443914	66/257 (26%)
		leucine-rich repeat	95..118	CDD:275380	5/33 (15%)
		leucine-rich repeat	119..142	CDD:275380	8/22 (36%)
		leucine-rich repeat	143..166	CDD:275380	6/22 (27%)
		leucine-rich repeat	167..190	CDD:275380	9/22 (41%)
		leucine-rich repeat	191..214	CDD:275380	5/22 (23%)
		leucine-rich repeat	215..238	CDD:275380	6/22 (27%)
		leucine-rich repeat	239..262	CDD:275380	0/22 (0%)
		leucine-rich repeat	263..286	CDD:275380	6/22 (27%)
		leucine-rich repeat	287..311	CDD:275380	11/23 (48%)
		LRR_8	310..371	CDD:404697	20/75 (27%)
		leucine-rich repeat	312..334	CDD:275380	6/24 (25%)
		leucine-rich repeat	337..360	CDD:275378	7/34 (21%)
		PCC	342..>420	CDD:188093	27/110 (25%)
		leucine-rich repeat	361..373	CDD:275378	4/11 (36%)
		Ig	430..514	CDD:472250
		Ig strand B	441..445	CDD:409421
		Ig strand C	454..458	CDD:409421
		Ig strand E	480..484	CDD:409421
		Ig strand F	494..499	CDD:409421
		Ig strand G	507..510	CDD:409421