DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7702 and lingo3

DIOPT Version :9

Sequence 1:NP_650740.1 Gene:CG7702 / 42242 FlyBaseID:FBgn0038638 Length:537 Species:Drosophila melanogaster
Sequence 2:XP_004911049.2 Gene:lingo3 / 100497438 XenbaseID:XB-GENE-6051175 Length:605 Species:Xenopus tropicalis


Alignment Length:494 Identity:108/494 - (21%)
Similarity:166/494 - (33%) Gaps:175/494 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   163 PIGLRDLDLSHNRIVRLDRRLFEHTPHLTKLNLAYNKLSSLDEATTASIGSVATLQRLDLSHNGL 227
            |...|.||||.|||..|:...|.....|.:::|:.|.:|:::....|::   ..||.|.|..|.|
 Frog    58 PSETRLLDLSKNRIRCLNPGDFSPYSLLEEVDLSENIISTIEPGAFANL---FFLQILKLKGNQL 119

  Fly   228 MTLPAQLFSKLTSLRFLDVSGNEF----------------------------------------- 251
            ..:|..:|:||::|..||:|.|:.                                         
 Frog   120 KLIPTGVFTKLSNLTLLDISENKIVILLDFMFQDLRSLKSLEVGDNDLLYISQKAFYGLVSLDQL 184

  Fly   252 --------STMPASLQLL-GKSLVQLNLAGNAFLSLKENSLQGLVSLKRLNISSMP--------- 298
                    |..|.||..| |..:::|...|  ..||:|.:.|.|.:||.|.:.|.|         
 Frog   185 TIEKCNLTSISPESLSYLQGLEVLRLRYLG--INSLEEQNFQKLYNLKELELESWPLLEDVCNTA 247

  Fly   299 --------------SLRSLEKGAL-NLPALEHLDCSRN-----------------------SKLE 325
                          :|.|:...|| |:..||:|:.|.|                       :.|.
 Frog   248 FQGLNLTSLSITYTNLTSVPSAALRNMVYLEYLNLSFNPIRIIQRGAFKDLVRLRELHIVGAFLS 312

  Fly   326 RLELADLLSSRNLSQLDLSWNALTTLVINATGSSNNSSNSTNETWPRLRRMSISGNPWYCSCELF 390
            .:|....|..|.:..|::|.|.|.||..:|..|.|.           |..:.:..||..|.|.|.
 Frog   313 TVESQAFLGLRQIRLLNVSNNLLATLEESAFQSVNT-----------LETLRVDDNPLACDCRLL 366

  Fly   391 KALELIGLNHIDREWDGTEARCETPYLLAGS-----PLSNLTAERICK--MVIPKKYREV----- 443
            ..|:    ......:|..:..|.:|..:.|:     |.|.|.....|:  .:..:|.:.:     
 Frog   367 WILQ----RRKTLNFDNHQPVCASPAKIQGNALRDFPDSILFEHFTCQKPKIRDRKLQHITAHEG 427

  Fly   444 ---------DEEPPRFL-----RRHYIILTAIIASIVLVIGLVIGFVVVCVRRRLKGSDYGVQPI 494
                     |.||...:     :|..|...::..|.||                    ..|...|
 Frog   428 QPVSFHCRADGEPVPLIVWVSPQRRMITSRSVGRSTVL--------------------PEGTLEI 472

  Fly   495 RYTSVR------------GSNLSQFSQLQPVSVASKFNN 521
            ||..|:            |.|.:.|:.|...|..|.::|
 Frog   473 RYAQVQDSGTYICIATNAGGNDTYFATLTVKSDNSPYSN 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7702NP_650740.1 leucine-rich repeat 110..131 CDD:275380
LRR_RI <123..267 CDD:238064 37/153 (24%)
leucine-rich repeat 132..165 CDD:275380 1/1 (100%)
LRR_8 165..227 CDD:290566 20/61 (33%)
leucine-rich repeat 166..189 CDD:275380 10/22 (45%)
leucine-rich repeat 190..213 CDD:275380 5/22 (23%)
LRR_8 216..273 CDD:290566 22/106 (21%)
leucine-rich repeat 217..240 CDD:275380 10/22 (45%)
leucine-rich repeat 241..264 CDD:275380 11/72 (15%)
LRR_8 263..321 CDD:290566 21/81 (26%)
leucine-rich repeat 265..288 CDD:275380 7/22 (32%)
leucine-rich repeat 289..312 CDD:275380 10/46 (22%)
leucine-rich repeat 313..337 CDD:275380 8/46 (17%)
lingo3XP_004911049.2 LRR 41..359 CDD:227223 74/316 (23%)
leucine-rich repeat 61..84 CDD:275380 10/22 (45%)
leucine-rich repeat 85..108 CDD:275380 5/25 (20%)
leucine-rich repeat 109..132 CDD:275380 10/22 (45%)
leucine-rich repeat 133..156 CDD:275380 5/22 (23%)
leucine-rich repeat 157..180 CDD:275380 0/22 (0%)
leucine-rich repeat 181..204 CDD:275380 5/22 (23%)
leucine-rich repeat 205..228 CDD:275380 7/24 (29%)
leucine-rich repeat 229..252 CDD:275380 5/22 (23%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..298 CDD:275380 5/20 (25%)
leucine-rich repeat 301..324 CDD:275380 3/22 (14%)
leucine-rich repeat 325..345 CDD:275380 7/19 (37%)
PCC 329..>399 CDD:188093 19/84 (23%)
Ig 413..502 CDD:416386 18/108 (17%)
Ig strand A' 419..423 CDD:409353 0/3 (0%)
Ig strand B 429..438 CDD:409353 0/8 (0%)
Ig strand C 443..448 CDD:409353 0/4 (0%)
Ig strand C' 451..453 CDD:409353 1/1 (100%)
Ig strand D 462..465 CDD:409353 1/2 (50%)
Ig strand E 468..475 CDD:409353 3/6 (50%)
Ig strand F 481..489 CDD:409353 0/7 (0%)
Ig strand G 492..502 CDD:409353 3/9 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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