Protein Alignment Cpsf73 and Snm1

DIOPT Version :10

• Sequence 1: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 125/645 - (19%)
• Similarity: 214/645 - (33%)
• Gaps: 231/645 - (35%)

  Fly     7 DARMPDEESDLLQI-----------------------KPLGAGQEVGRSCIMLEFKGKKIMLDCG 48
            :|::.:...||::|                       .|||...:.|  .:..:.|.|    .|.
  Fly   207 EAKLSNSSLDLVEISPGPNKSPTNNFYRSSPAAITKESPLGKNSKKG--TVRKQRKPK----PCP 265

  Fly    49 IHPGLSGMDALPYVDLIEADEIDLL---FISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYR 110
            .:..:.|....  ||..:..||:.:   |::|||.||...|.        |..|...:.:....|
  Fly   266 PYKVVEGTSFC--VDGFQFGEIEGVTHYFLTHFHADHYIGLT--------KKFCHPLYVSPISAR 320

  Fly   111 WMLSDYIKISNISTEQMLYTEADLEASMEKIETINFHEERDVMGVRFCAYIAGHVLGAAMFMIEI 175
             ::..:||:..                 ..|..|:..:..||.||:..|..|.|..||.||..::
  Fly   321 -LVRTFIKLDE-----------------THIHEIDVDQTLDVDGVQVTALEANHCPGALMFFFKL 367

  Fly   176 -AGIKILYTGDFSRQEDRHLMAAEVPPMKPDVLITESTYGTHIHE--KREDRENRFTSLVQKIVQ 237
             :|..||:||||....|...:.........|:|..::||....::  .:.:..:|...||:..::
  Fly   368 SSGECILHTGDFRASADMESLPIFWNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDLVRAFLE 432

  Fly   238 QGG--RCLIPV--FALGRAQELLLILDEF----WSQN-----------PDLHEIPIYYASSLAKK 283
            :..  |.||..  :.:|:.:..|.:..||    |:::           |||..:
  Fly   433 KNAAKRILIVCGSYVIGKEKIWLALAKEFTMRVWTESNRSTAVRCLNWPDLDSV----------- 486

  Fly   284 CMAVYQTYINAMNDRIRRQIAVNNPFVFRHISNLKGIDH---FEDIGPCVIMASPGMMQSGLSRE 345
                      ...||....:.|   .....||....:|:   |||....::    |:..||
  Fly   487 ----------LTEDRSGANLHV---IAMGKISYPSLVDYFTEFEDQYDMLL----GIRPSG---- 530

  Fly   346 LFESWCTDPKNGVIIAGYCVEGTLAKAVLSEP---EEITTLSGQKLPLNMSVDYISFSAHTDYQQ 407
                |   .||                  |:|   :.|:|:.            |.:|.|:.|::
  Fly   531 ----W---EKN------------------SKPSYGKRISTIG------------IEYSEHSSYKE 558

  Fly   408 TSEFIRLLKPTHVV---------LVHGE--------QNEMSRLK----------LALQREYEADA 445
            ...|:|.|||..|:         .|.||        :...|.|:          ||..:...|..
  Fly   559 LERFVRFLKPKRVISTVPVGRDLYVTGEVPIRWYKYEGRASMLRTGFQPSISTFLATPKRAFAKF 623

  Fly   446 STDIK-FYNP---------------------RNTHAVDLYFRGEKTAKVMGSLAAK--------- 479
            |.|.: |.:|                     ...|...:....|:..:....:..|
  Fly   624 SADTEMFLSPVDENASKGSEDKKDDDRESVVPTNHVTIISDTPEECFQTDSKIPVKNEPLAPDTS 688

  Fly   480 -NSEVGSKLSGV-----LVKRDFKYHLLAP----------SDLGKYTDMSMSVVTQRQSI 523
             |||:.::|:.:     .|:.|.|...:||          .|..:.||.::..|.:.|::
  Fly   689 PNSEIVAQLNAMESEIPYVEIDIKNETIAPDAVLIPRVPTEDTFQSTDCNVIGVQKSQAV 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf73	NP_650738.1	CPSF3-like_MBL-fold	18..211	CDD:293850	48/219 (22%)
		YSH1	19..427	CDD:440849	96/478 (20%)
		CPSF73-100_C	486..680	CDD:463330	11/53 (21%)
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	46/189 (24%)
		DRMBL	481..578	CDD:429512	32/165 (19%)