Protein Alignment Cpsf73 and Dclre1a

DIOPT Version :10

• Sequence 1: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001099671.1
• Gene: Dclre1a / 292127
• RGDID: 1306156
• Length: 1026
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 97/499 - (19%)
• Similarity: 152/499 - (30%)
• Gaps: 203/499 - (40%)

  Fly    18 LQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDLIEADEID---LLFISHFH 79
            :.|.....|.|..|:|...    |:|       || :|..    ||..:..||:   ..|::|||
  Rat   672 VNISESSGGGESRRTCPFY----KRI-------PG-TGFT----VDAFQYGEIEGCTAYFLTHFH 720

  Fly    80 LDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKISNISTEQMLYTEADLEASMEKIETI 144
            .||...|          .:.|    |:.||         .|.| |..:|  :..|....:.|..:
  Rat   721 SDHYAGL----------SKDF----TRPIY---------CSEI-TGSLL--KKKLRVQEQYIHQL 759

  Fly   145 NFHEERDVMGVRFCAYIAGHVLGAAMFMIEIA-GIKILYTGDFSRQE--DRHLMAAEVPPMKPDV 206
            ....|..|.||:.....|.|..||.|.:.::. |...|:||||....  :|.|:|:.    |...
  Rat   760 PMDTECIVDGVKVVLLDANHCPGATMILFQLPNGAVTLHTGDFRADPSMERSLLASR----KVHT 820

  Fly   207 LITESTYGTHIHEKREDRENRFTSLVQKI----------VQQGGRCLI--PVFALGRAQELLLIL 259
            |..::||.:        .|..|.|..:.|          |....|.||  ..:.:|:.:..|.|.
  Rat   821 LFLDTTYCS--------PEYTFPSQQEAIQFAINTAFEAVTLNPRALIVCGTYCIGKEKVFLAIA 877

  Fly   260 DEFWSQ----------------------------NPDLHEIPIYYAS-----SLAKKCMAVYQTY 291
            |...|:                            |..:|.:|:...:     :..|||...:.
  Rat   878 DVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCNSLVHLLPMMQINFKGLQNHLKKCGGKFD-- 940

  Fly   292 INAMNDRIRRQIAVNNPFVFRHISNLKGIDHFEDIGPCVIMASPGMMQSGLSRELFESWCTDPKN 356
                      ||....|..:.|.:|:..|   .||.|                        ..|.
  Rat   941 ----------QILAFRPTGWTHSNNITSI---ADITP------------------------QTKG 968

  Fly   357 GVIIAGYCVEGTLAKAVLSEPEEITTLSGQKLPLNMSVDYISFSAHTDYQQTSEFIRLLKPTHVV 421
            .:.|.|                                  |.:|.|:.|.:...|::.|||..::
  Rat   969 NIAIYG----------------------------------IPYSEHSSYLEMKRFVQWLKPQKII 999

  Fly   422 LVHGEQNEMSRLKLALQREYEADASTDIKFYNPRNTHAVDLYFR 465
                                   .:.::..:..|||  ::.||:
  Rat  1000 -----------------------PTVNVGTFQSRNT--MEKYFK 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf73	NP_650738.1	CPSF3-like_MBL-fold	18..211	CDD:293850	51/198 (26%)
		YSH1	19..427	CDD:440849	92/458 (20%)
		CPSF73-100_C	486..680	CDD:463330
Dclre1a	NP_001099671.1	metallo-hydrolase-like_MBL-fold	675..830	CDD:451500	52/208 (25%)
		DRMBL	900..1005	CDD:429512	26/200 (13%)