Protein Alignment Cpsf73 and cpsf-3

DIOPT Version :10

• Sequence 1: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_502553.2
• Gene: cpsf-3 / 178285
• WormBaseID: WBGene00013460
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 368/717 - (51%)
• Similarity: 482/717 - (67%)
• Gaps: 74/717 - (10%)

  Fly    13 EESDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDLIEADEIDLLFISH 77
            :.||.|...|||:||||||||.:||:|||::|||||:||||.|:||||:||.:|.:.||||.|:|
 Worm     6 DNSDSLCFTPLGSGQEVGRSCHLLEYKGKRVMLDCGVHPGLHGVDALPFVDFVEIENIDLLLITH 70

  Fly    78 FHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKISNIS--TEQMLYTEADLEASMEK 140
            |||||||||||.|.||:|:|:||||||||||||.:|.||::||...  ....||||.|||.||.|
 Worm    71 FHLDHCGALPWLLQKTAFQGKCFMTHATKAIYRMLLGDYVRISKYGGPDRNQLYTEDDLEKSMAK 135

  Fly   141 IETINFHEERDVMGVRFCAYIAGHVLGAAMFMIEIAGIKILYTGDFSRQEDRHLMAAEVPPMKPD 205
            ||||:|.|:::|.|:||..|:|||||||..|||||||:::|||||||..|||||.|||:||:.|.
 Worm   136 IETIDFREQKEVNGIRFWPYVAGHVLGACQFMIEIAGVRVLYTGDFSCLEDRHLCAAEIPPITPQ 200

  Fly   206 VLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILDEFWSQNPDLH 270
            ||||||||||..||.|..||.|||.:|..||.:|||||||.||:|.||||:|||||:|..:.:||
 Worm   201 VLITESTYGTQTHEDRAVREKRFTQMVHDIVTRGGRCLIPAFAIGPAQELMLILDEYWESHQELH 265

  Fly   271 EIPIYYASSLAKKCMAVYQTYINAMNDRIRRQIAVNNPFVFRHISNLKGIDHFEDIGPCVIMASP 335
            :||:|||||||||||:||||::|.||.||::||||.|||:|:|:|.|:|:|.|||.||||::|:|
 Worm   266 DIPVYYASSLAKKCMSVYQTFVNGMNSRIQKQIAVKNPFIFKHVSTLRGMDQFEDAGPCVVLATP 330

  Fly   336 GMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVLSEPEEITTLSGQKLPLNMSVDYISFS 400
            ||:|||.|||||||||.|.|||.|||||||||||||.:|||||||.:|||:|||:.|.|.|:|||
 Worm   331 GMLQSGFSRELFESWCPDTKNGCIIAGYCVEGTLAKHILSEPEEIVSLSGEKLPMRMQVGYVSFS 395

  Fly   401 AHTDYQQTSEFIRLLKPTHVVLVHGEQNEMSRLKLALQREYEADASTDIKFYNPRNTHAVDLYFR 465
            |||||.|||.|::.|||.|:||||||.:||||||..::|::: |.:..|:.:|||||..:.|.||
 Worm   396 AHTDYHQTSNFVKALKPPHLVLVHGELHEMSRLKSGIERQFQ-DDNIPIEVHNPRNTERLQLQFR 459

  Fly   466 GEKTAKVMGSLAAKNSEVGSKLSGVLVKRDFKYHLLAPSDLGKYTDMSMSVVTQRQSIPWGSSLS 530
            |||||||:|.||.:..|....:||||||.:|.|.::.|.:||.||.:.:|.:.||.|:.:..||.
 Worm   460 GEKTAKVIGKLAQRVPENNETISGVLVKNNFSYSIMVPEELGSYTSLRISSLEQRMSVHYSGSLK 524

  Fly   531 TLELLLDRIG-AGC----VEVLEAERK------LRVF-GCIELTV--EQKIIVMEWQATHVNDVY 581
            .|...|.::. ..|    :::.|..:|      :.|| |.:.:||  ...::|:.|.:..|.|:|
 Worm   525 LLIFNLQQLNDDACLIQNIKLKEISKKGSVTQAITVFQGKVNVTVYGNDHVVVVRWDSNPVYDMY 589

  Fly   582 ADAVLACIMQSELG----------------GTNLKGATKQTKSED-----------SRF----RE 615
            ||:|:|.|:.::..                .|.::|..|....:|           ::|    |.
 Worm   590 ADSVVAAILHAQANPVPDKYLPSNSSFPQFNTAIEGMVKHICGDDVSIVMSERGLLAQFEEDGRR 654

  Fly   616 CLIETLQDTFGDNCVPKMFEGDLLPVTVSGKRAEINLETLAISCAEDDVLRQMLNTTVQKLHQTL 680
            .|:|      |.:..|.|..||                    ...:|.....:|....:|:.|.:
 Worm   655 LLVE------GSSDGPVMMGGD--------------------DPMDDPTTSHLLQNLTEKMRQIV 693

  Fly   681 VS 682
            .:
 Worm   694 TT 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf73	NP_650738.1	CPSF3-like_MBL-fold	18..211	CDD:293850	130/194 (67%)
		YSH1	19..427	CDD:440849	280/409 (68%)
		CPSF73-100_C	486..680	CDD:463330	56/238 (24%)
cpsf-3	NP_502553.2	CPSF3-like_MBL-fold	11..206	CDD:293850	130/194 (67%)
		YSH1	13..421	CDD:440849	279/407 (69%)
		CPSF73-100_C	477..694	CDD:215023	56/242 (23%)