Protein Alignment Cpsf73 and CPSF2

DIOPT Version :10

• Sequence 1: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_061504328.1
• Gene: CPSF2 / 1273485
• VectorBaseID: AGAMI1_004813
• Length: 790
• Species: Anopheles gambiae
• Alignment Length: 688
• Identity: 147/688 - (21%)
• Similarity: 284/688 - (41%)
• Gaps: 115/688 - (16%)

  Fly    15 SDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCG----IHPGLSGMDALPYVDLIEADEIDLLFI 75
            :.::::..:....:....|.:|:....:|:||||    ...|.. .:...||..|:|     :.:
Mosquito     2 TSIIKMHAISGAMDESPPCYILQVDDVRILLDCGWDEKFDQGFI-KEIKKYVHTIDA-----VLL 60

  Fly    76 SHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYR----WMLSDYIKISNISTEQMLYTEADLEA 136
            |:....|.||||:.:.|...  .| ..:||..:|:    :|...::...|:. :..|::..|::|
Mosquito    61 SYPDGSHLGALPYLVGKLGL--NC-PIYATIPVYKMGQMFMYDMFMSHYNMH-DFDLFSLDDVDA 121

  Fly   137 SMEKIETINFHEERDVMGVRFCAYI----AGHVLGAAMF-MIEIAGIKILYTGDFSRQEDRHLMA 196
            :.:||..:.:::...:.|..:...|    |||::|..:: ::::....|:|..||:.:::|||..
Mosquito   122 AFDKIVQLKYNQSVAMKGKGYGITITPLPAGHLIGGTIWKIVKVGEEDIVYATDFNHKKERHLNG 186

  Fly   197 AEVPPM-KPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILD 260
            .|:..: :|.:|||::....:...:|..|:.:|.:.:.:.::..|..|:.|...||..||..:||
Mosquito   187 CELEKLQRPSLLITDAYNARYQQARRRARDEKFMTNILQTLRNNGNVLVTVDTAGRVLELAHMLD 251

  Fly   261 EFW-SQNPDLHEIPIYYASSLAKKCMAVYQTYINAMNDRIRRQI--AVNNPFVFRHISNLKGIDH 322
            :.| ::...|....:...::.:...:...::.|..|:|::.:..  |.||||.|:|:.....:..
Mosquito   252 QLWKNKESGLMAYSLALLNNQSYNVVEFAKSQIEWMSDKLMKSFEGARNNPFTFKHLRLCHTMAD 316

  Fly   323 FEDI-GPCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVL------------ 374
            ...: .|.|::||...::||.|||||..|..:..|.:||......||||:.::
Mosquito   317 LAKVPSPKVVLASSPDLESGFSRELFIQWAPNASNSIIITSRSSPGTLARDLIENGGNGRKIEMD 381

  Fly   375 ---------SEPEEITTLSGQKLPLNMSV---DYISFSAHTDYQQTSEFIRLLKPTHVVLVHGEQ 427
                     :|.||.....|:|  ||.|:   |....|:.:|.:..   :.::...|.::|..|.
Mosquito   382 IRRRVELEGAELEEYMRTEGEK--LNRSIKKRDLDESSSDSDDELE---MNVITGKHDIVVRPEG 441

  Fly   428 N------EMSRLKLALQREYEADASTDI--KFYNPRNTHAVDLYFRGEKTAKVMGSLAAKNSEVG 484
            .      :.|:...|:...:|.....|.  :...|.:...|||   |.:|          |....
Mosquito   442 RSHTGFFKSSKKNYAMFPFHEEKIKYDEYGEIIQPDDYRMVDL---GPET----------NGGDD 493

  Fly   485 SKLSGVLVKRDFKYHLLAPSDLGKYTDMSMSVVTQRQSIPWGSSLSTLELLLDRIGAGCVEVLEA 549
            :|.:|.:...|.|..   ..|.....|.....|..|:.|...:.:..::......|...:::|..
Mosquito   494 NKENGGIKTEDIKKE---KEDEVTVLDKPTKCVQSRKPIEVNAQVQFIDFEGRSDGESLLKILSQ 555

  Fly   550 ERKLRVFGCIELTVEQKIIVMEWQA--THVNDVYADAVLACIMQSELGGTNLKGATKQTKSEDSR 612
            .|..||           ::|....|  :|:.:.....:.|.:.....|  .:..||.:|.....|
Mosquito   556 LRPRRV-----------VVVRGSPANTSHIAEHCQQNIGARVFTPNRG--EIIDATTETHIYQVR 607

  Fly   613 FRECLIETLQDTFGDNCVPKMFEGDLLPVTVSGKRAEI 650
            ..|.|:..|:           |:        .||.||:
Mosquito   608 LTEALVSQLE-----------FQ--------KGKDAEV 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf73	NP_650738.1	CPSF3-like_MBL-fold	18..211	CDD:293850	48/206 (23%)
		YSH1	19..427	CDD:440849	104/449 (23%)
		CPSF73-100_C	486..680	CDD:463330	31/167 (19%)
CPSF2	XP_061504328.1	None