DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and RIE1

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_011766.3	Gene:	RIE1 / 853165	SGDID:	S000003482	Length:	781	Species:	Saccharomyces cerevisiae

Alignment Length:	140	Identity:	40/140 - (28%)
Similarity:	69/140 - (49%)	Gaps:	21/140 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYE 81
            ::|||.|....:..:|..:||:.||:||:||::|:..|:|.|:||..|.....|...::.|||..
Yeast   196 NIFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNGYGFISYPLGSQASLCIKELNGRT 260

  Fly    82 IGGRTLRVDNAC--TEKSRMEMQQLLQGPQVEN---------PYGEPCEPEDAPELITKTVASLP 135
            :.|.||.::...  .|:.|:....:.:....:|         ||.   .||....|||
Yeast   261 VNGSTLFINYHVERKERERIHWDHVKENNNDDNFRCLFIGNLPYH---NPEKVETLIT------- 315

  Fly   136 PEQMYELMKQ 145
            |:::.|::|:
Yeast   316 PKEVIEVIKK 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	29/96 (30%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	27/73 (37%)
		CSTF2_hinge	112..190	CDD:291025	11/43 (26%)
		CSTF_C	377..416	CDD:291002
RIE1	NP_011766.3	PABP-1234	195..757	CDD:130689	40/140 (29%)
RIE1	NP_011766.3	RRM3_CELF1-6	542..634	CDD:409797
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900