DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and RNA15

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_011471.1	Gene:	RNA15 / 852838	SGDID:	S000003012	Length:	296	Species:	Saccharomyces cerevisiae

Alignment Length:	263	Identity:	65/263 - (24%)
Similarity:	124/263 - (47%)	Gaps:	45/263 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGY 80
            |.|::|:|||:.|||::.::.|.||||::||::||.::|:.||:.|.|::|.|::.||:||||||
Yeast    18 RVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGY 82

  Fly    81 EIGGRTLRVD-NACTEKSRMEMQQLLQ-------------------GPQVENPYGEPCEPEDAPE 125
            ::|.|.|:.. ::.::.|.:..||..|                   ||..:|........:..||
Yeast    83 QLGSRFLKCGYSSNSDISGVSQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPE 147

  Fly   126 L----------------ITKTVASLPPEQMYELMKQMKLCIVSNPSEARQMLMLNPQLAYALLQA 174
            |                |:..:|..|.|...:.:::.:....::|.:|..:|.|.|||::...:.
Yeast   148 LPSGIDVNINMTTPAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLSFVTAEL 212

  Fly   175 MVVMRIVDPQQALGMLFKANQMPPVLGGNPHQGPGNHTMMGQQ--------QVPQQQVQI-PQQQ 230
            ::...|......:.:..:..:.......|......:..::.:|        |:...|:.| |..:
Yeast   213 LLTNGICKVDDLIPLASRPQEEASATNNNSVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDDE 277

  Fly   231 QQA 233
            :.|
Yeast   278 RMA 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	42/115 (37%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	35/74 (47%)
		CSTF2_hinge	112..190	CDD:291025	16/93 (17%)
		CSTF_C	377..416	CDD:291002
RNA15	NP_011471.1	RRM_CSTF2_RNA15_like	18..94	CDD:409832	36/75 (48%)
RNA15	NP_011471.1	CSTF_C	255..291	CDD:405061	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346170
Domainoid	1	1.000	87	1.000	Domainoid score	I1852
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1265
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001914
OrthoInspector	1	1.000	-	-		oto99211
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	LDO	PTHR45735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2262
SonicParanoid	1	1.000	-	-		X1629
TreeFam	0	0.000	Not matched by this tool.
	12	11.820