DRSC/TRiP Functional Genomics Resources

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Protein Alignment CstF64 and TIAL1

DIOPT Version :10

Sequence 1:NP_477453.1 Gene:CstF64 / 42239 FlyBaseID:FBgn0027841 Length:419 Species:Drosophila melanogaster
Sequence 2:NP_001029097.1 Gene:TIAL1 / 7073 HGNCID:11804 Length:392 Species:Homo sapiens


Alignment Length:353 Identity:78/353 - (22%)
Similarity:125/353 - (35%) Gaps:105/353 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEI 82
            ||||::..|.|.|.:|..|:..|.:...::|.|..:||.||:||..:.::..|.:|:.::.|..:
Human   116 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL 180

  Fly    83 GGRTLRVDNACTE----KSRMEMQ-QLLQGPQVENPYGEPCEPEDAPELITKTVASLPPEQMYEL 142
            |||.:|.:.|..:    ||..|.. :.|:...|.|        :.:|:..|.....:......:|
Human   181 GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVN--------QSSPKNCTVYCGGIASGLTDQL 237

  Fly   143 MKQMKLCIVSNPSEARQMLMLNPQLAYALLQAMVVMRIVDPQQALGMLFKANQMPPVLGGNPHQG 207
            |:|     ..:|......:.:.|:..|:.      :|....:.|...:...|       |...:|
Human   238 MRQ-----TFSPFGQIMEIRVFPEKGYSF------VRFSTHESAAHAIVSVN-------GTTIEG 284

  Fly   208 PGNHTMMGQQQVPQ----QQVQIPQQQQQAPQPPMPVPGPGFPANVHPNDIDLRMVPGGPMPMDP 268
            .......|::....    |||...|..|.              :.|:.|               |
Human   285 HVVKCYWGKESPDMTKNFQQVDYSQWGQW--------------SQVYGN---------------P 320

  Fly   269 RMMGRGMDQDLRASLPNPVPPPLMDPRARAQMPP---------QQQQGVPQAPPAPYPSDPRQRP 324
            :..|:.|....                   |:||         ||..||.|:|.|.:......:|
Human   321 QQYGQYMANGW-------------------QVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQP 366

  Fly   325 MDPRLRAGPGPQQQAPPQGIPQAPPPTQ 352
                      ||.||||   |..|||.|
Human   367 ----------PQGQAPP---PVIPPPNQ 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CstF64NP_477453.1 RRM_CSTF2_CSTF2T 10..94 CDD:410072 26/75 (35%)
CSTF2_hinge 111..190 CDD:433869 11/78 (14%)
CSTF_C 377..416 CDD:464130
TIAL1NP_001029097.1 RRM1_TIAR 10..107 CDD:410028
RRM2_TIAR 113..192 CDD:410029 26/75 (35%)
RRM3_TIAR 222..294 CDD:241064 13/89 (15%)
Blue background indicates that the domain is not in the aligned region.

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