Protein Alignment CstF64 and TIA1

DIOPT Version :9

• Sequence 1: NP_477453.1
• Gene: CstF64 / 42239
• FlyBaseID: FBgn0027841
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_071505.2
• Gene: TIA1 / 7072
• HGNCID: 11802
• Length: 386
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 71/313 - (22%)
• Similarity: 117/313 - (37%)
• Gaps: 99/313 - (31%)

  Fly     4 KAQEQSIMDKSMRS-----VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCE 63
            |....|.:..:.||     ||||::..|.|.|.:|..|:..|.:...::|.|..:||.||:||..
Human    89 KDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVS 153

  Fly    64 YKDQETALSAMRNLNGYEIGGRTLRVDNACTE----KSRME------------------------ 100
            :.::..|.:|::.:.|..:|||.:|.:.|..:    ||..|
Human   154 FFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218

  Fly   101 -------MQQLLQGPQVENPYGEPCEPEDAPELITKTVASLPPEQMYELMKQMKLCIVSNPSEAR 158
                   .:||::  |..:|:|:..|            ..:.|::.|..::     ..|:.|.|.
Human   219 GGVTSGLTEQLMR--QTFSPFGQIME------------IRVFPDKGYSFVR-----FNSHESAAH 264

  Fly   159 QMLMLNPQLAYALLQAMVV--------MRIVDPQQALGMLFKANQMP-PVLGGNPHQGPGNHTMM 214
            .::.:|.    ..::..||        :.:::|.|      :.||:. |...|...|..||...:
Human   265 AIVSVNG----TTIEGHVVKCYWGKETLDMINPVQ------QQNQIGYPQPYGQWGQWYGNAQQI 319

  Fly   215 GQQ-----QVPQ--------QQVQIPQQQQQAP--------QPPMPVPGPGFP 246
            ||.     |||.        .|....|.|..||        |||....|...|
Human   320 GQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSMLP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	34/138 (25%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	25/73 (34%)
		CSTF2_hinge	112..190	CDD:291025	13/85 (15%)
		CSTF_C	377..416	CDD:291002
TIA1	NP_071505.2	RRM1_TIA1	8..81	CDD:410027
		RRM2_TIA1	104..181	CDD:410030	25/76 (33%)
		RRM3_TIAR	214..286	CDD:241064	14/94 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..386		5/19 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810