DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and SNRNP70

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_003080.2	Gene:	SNRNP70 / 6625	HGNCID:	11150	Length:	437	Species:	Homo sapiens

Alignment Length:	98	Identity:	31/98 - (31%)
Similarity:	55/98 - (56%)	Gaps:	3/98 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADKAQEQSIMDKSMRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYK 65
            |.|...:.:....:.:::||..:.|:.||.||:..|...||:..:.:|:.:.||||:|:.|.||:
Human    88 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYE 152

  Fly    66 DQETALSAMRNLNGYEIGGRTLRVDNACTEKSR 98
            .:....||.::.:|.:|.||.:.||   .|:.|
Human   153 HERDMHSAYKHADGKKIDGRRVLVD---VERGR 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	29/86 (34%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	27/73 (37%)
		CSTF2_hinge	112..190	CDD:291025
		CSTF_C	377..416	CDD:291002
SNRNP70	NP_003080.2	U1snRNP70_N	3..93	CDD:403437	2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..79
		Required for interaction with U1 RNA. /evidence=ECO:0000269\|PubMed:2467746	92..202		29/94 (31%)
		RRM_snRNP70	102..187	CDD:409682	29/84 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810