DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and Srsf6

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001014207.2	Gene:	Srsf6 / 362264	RGDID:	1359241	Length:	339	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	32/142 - (22%)
Similarity:	55/142 - (38%)	Gaps:	46/142 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 MRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNG 79
            |..|::|.:.|...|:.::..||..|.:|.:.|        ..|:||.|::|...|..|:..||.
  Rat     1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDL--------KNGYGFVEFEDSRDADDAVYELNS 57

  Fly    80 YEIGGRTLRVDNACTEKSRMEMQQLLQGPQVE-----------------------NPYGEPCEPE 121
            .|:.|..:.|::|             :||:.:                       :.||.|...|
  Rat    58 KELCGERVIVEHA-------------RGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTE 109

  Fly   122 DAPELITKTVAS 133
              ..||.:.::|
  Rat   110 --YRLIVENLSS 119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	25/119 (21%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	21/73 (29%)
		CSTF2_hinge	112..190	CDD:291025	7/22 (32%)
		CSTF_C	377..416	CDD:291002
Srsf6	NP_001014207.2	RRM_SF	1..72	CDD:418427	23/91 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..103		0/27 (0%)
		RRM2_SRSF6	110..182	CDD:410159	3/10 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..339
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900