DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and srsf5a

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_957161.1	Gene:	srsf5a / 335396	ZFINID:	ZDB-GENE-030131-7336	Length:	259	Species:	Danio rerio

Alignment Length:	147	Identity:	33/147 - (22%)
Similarity:	61/147 - (41%)	Gaps:	34/147 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEI 82
            ||:|.:...|.|..:::.|...|.:        ||.....||||.|:.|...|..|:..|||.|:
Zfish     6 VFIGRLSPHARERDVEKFFKGYGRI--------REINLKNGFGFVEFDDYRDADDAVYELNGKEL 62

  Fly    83 GGRTLRVDNACTEKSRMEMQQLLQGPQV-----------------ENPYGEPCEPEDAPELITKT 130
            ....:.:::|.:.:.|.      .||.:                 .:.||.|...|.  .:|.:.
Zfish    63 CSERVTIEHARSRRGRG------GGPGMGGRFSPRFGGYRQSRSGGSRYGPPVRTEH--RIIVEN 119

  Fly   131 VAS-LPPEQMYELMKQM 146
            ::| :..:.:.:||:::
Zfish   120 LSSRISWQDLKDLMRKV 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	25/110 (23%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	21/73 (29%)
		CSTF2_hinge	112..190	CDD:291025	8/36 (22%)
		CSTF_C	377..416	CDD:291002
srsf5a	NP_957161.1	RRM1_SRSF4_like	5..72	CDD:240783	21/73 (29%)
srsf5a	NP_957161.1	RRM2_SRSF4_like	113..184	CDD:241044	4/26 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900