DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and U2af50

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001245708.1	Gene:	U2af50 / 32602	FlyBaseID:	FBgn0005411	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	38/158 - (24%)
Similarity:	66/158 - (41%)	Gaps:	33/158 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SIMDKSMRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSA 73
            :::..|...:|:|.:|....::::||:....|.:.:..||.|..:|..||:.||||.|......:
  Fly   211 TVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQS 275

  Fly    74 MRNLNGYEIGGRTLRVDNA------CTEKSRMEMQQLLQGPQVENPYGEPCEPEDAPELITKTVA 132
            :..|||.::|.:.|.|..|      ....:......:||.|.:.|                 .|.
  Fly   276 IAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVMLQVPGLSN-----------------VVT 323

  Fly   133 SLPPEQMYELMKQMKLCIVS--NPSEAR 158
            |.||.::        ||:::  .|.|.|
  Fly   324 SGPPTEV--------LCLLNMVTPDELR 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	28/104 (27%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	23/73 (32%)
		CSTF2_hinge	112..190	CDD:291025	10/49 (20%)
		CSTF_C	377..416	CDD:291002
U2af50	NP_001245708.1	RRM1_U2AF65	103..184	CDD:240676
		RRM2_U2AF65	218..294	CDD:240677	23/75 (31%)
		RRM3_U2AF65	328..415	CDD:240678	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451801
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930