DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CstF64 and SPAC644.16

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_593884.1	Gene:	SPAC644.16 / 2543462	PomBaseID:	SPAC644.16	Length:	422	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	122/461 - (26%)
Similarity:	183/461 - (39%)	Gaps:	113/461 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEI 82
            |:|||||||..||::.:||.:.|||.|.:||.|.|||:|||:|||||.|..||.||:||||.|:.
pombe     7 VYVGNIPYEMAEEQVIDIFKQSGPVKSFQLVIDPESGQPKGYGFCEYHDPATAASAVRNLNNYDA 71

  Fly    83 GGRTLRVDNACTEKSRMEMQQLLQGPQ---------------VENPYGE--PCEPEDAP------ 124
            |.|.||||....::.| .:.:|| ||.               ..|.:|.  |.:|...|
pombe    72 GTRRLRVDFPTADQIR-RLDKLL-GPSRYGYYPQSYANQSYTYGNNFGSYPPTQPSTQPLPQSYG 134

  Fly   125 ----------------------ELITKTVASLPPEQMYELMKQMKLCIVSNPSEARQMLMLNPQL 167
                                  :.:.:.:|.|.|.::..::..:|...:..|.:|.|:...||||
pombe   135 YPSYPPAGYRGGSARPSGVLANDEVYRVLAQLAPNEIDYMLSAIKALCLEAPEQAAQLFETNPQL 199

  Fly   168 AYALLQAMVVMRIVDPQQALGMLFKANQMPPVLGGNPHQGPGNHTMMGQQQVPQQQVQIPQQQQQ 232
            :||:.|||::.|.........:|..|.                             |.:|..|:
pombe   200 SYAVFQAMLMKRYTSESVVADLLIPAG-----------------------------VNLPGAQE- 234

  Fly   233 APQPPMPVPGPGFPANVHPNDIDLRMVPGGPMPMDPRMMGRGMDQDLRAS-------LPNPVPPP 290
                    |..|:.:.:|...   ..|| ||:.:.....||........|       .|....|.
pombe   235 --------PNRGYFSPMHTYS---SAVP-GPISVPSAPYGRASSTIAEVSPMYGSHAAPYASTPS 287

  Fly   291 LMDPRARAQMPPQQQQGVPQAPPAPYPSDPRQRPMDPRL-RAGPG------PQQQAPPQGIPQAP 348
            .....:|...|....  ||.:|...:|:.....|..|.. .|.|.      .....|..|..::|
pombe   288 AAVGSSRGSTPASAT--VPISPARGFPTTSAYNPAPPAYGMANPAYGSTGIRSSSIPSSGSIRSP 350

  Fly   349 PPTQQQQAAAQQLQSRLGAHGVLPSDASDQE---KAALIMQVLQLSDEQIAQLPSEQRVSIVMLK 410
            ..|.....|...     ..:.:..:.|:..|   |||||.|::.|:|:||..||.:|:..|:.::
pombe   351 SLTTTSAQATTN-----ATNNITTTTAAQDENATKAALIAQLMALTDDQINVLPPDQKERILQIR 410

  Fly   411 EQIAKS 416
            :.:..|
pombe   411 QALPSS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	51/108 (47%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	46/73 (63%)
		CSTF2_hinge	112..190	CDD:291025	22/107 (21%)
		CSTF_C	377..416	CDD:291002	15/41 (37%)
SPAC644.16	NP_593884.1	RRM	<3..>116	CDD:223796	52/110 (47%)
		RRM_CSTF2_RNA15_like	7..81	CDD:240844	46/73 (63%)
		CSTF2_hinge	150..222	CDD:291025	17/71 (24%)
		CSTF_C	380..413	CDD:291002	14/32 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	95	1.000	Domainoid score	I1940
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1422
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001914
OrthoInspector	1	1.000	-	-		otm47088
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	O	PTHR45735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2262
SonicParanoid	1	1.000	-	-		X1629
TreeFam	1	0.960	-	-
	12	11.850