DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and ctf1

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_596669.1	Gene:	ctf1 / 2541018	PomBaseID:	SPBC3B9.11c	Length:	363	Species:	Schizosaccharomyces pombe

Alignment Length:	500	Identity:	98/500 - (19%)
Similarity:	153/500 - (30%)	Gaps:	254/500 - (50%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEI 82
            ||||||||:.:|:::.|||::||||.:.|||.|.|:|..||:||||:.|.||...|:|.||..|:
pombe     9 VFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPETGSGKGYGFCEFFDSETTAMAVRKLNNSEL 73

  Fly    83 GGRTLRVD--------------------------------------------------------- 90
            |.|.:||:
pombe    74 GPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQNAHESSYNSRFIPPVLHSTSSLPASQGGGMPS 138

  Fly    91 ---------------------------------------------NACT---EKSRMEMQQLLQG 107
                                                         ||.|   .||.........|
pombe   139 PAIYSSSMATNLNKNINSTSVPAYNFHNSMTSDFDSASQPHTDAYNARTFQYNKSSQNKGDYTSG 203

  Fly   108 PQVENPYGEPCEPEDAPELITKTVASLPPEQMYELMKQMKLCIVSNPSEARQMLMLNPQLAYALL 172
            ..:.||...|..|.     :.:.:::...:::..::.:::..:...|.|||::|:.||.|.||..
pombe   204 TSISNPTSIPLAPS-----VVQVLSTFSAQELLNMLSKLQTVVHIAPEEARRLLIANPALPYAAF 263

  Fly   173 QAMVVMRIVDPQQALGMLFKANQMPPVLGGNPHQGPGNHTMMGQQQVPQQQVQIPQQQQQAPQPP 237
            |||::|.:||          ||.:                         |||.:..:.:
pombe   264 QAMLLMNLVD----------ANVL-------------------------QQVVVAVKNK------ 287

  Fly   238 MPVPGPGFPANVHPNDIDLRMVPGGPMPMDPRMMGRGMDQDLRASLPNPVPPPLMDPRARAQMPP 302
                      |:|                                          .|.:....||
pombe   288 ----------NMH------------------------------------------QPASATSSPP 300

  Fly   303 QQQQGVPQAPPAPYPSDPRQRPMDPRLRAGPGPQQQAPPQGIPQAPPPTQQQQAAAQQLQSRLGA 367
                                                :.||.||.:...:||...:.|
pombe   301 ------------------------------------SVPQKIPSSNHKSQQANGSDQ-------- 321

  Fly   368 HGVLPSDASDQEKAALIMQVLQLSDEQIAQLPSEQRVSIVMLKEQ 412
                   .::.::.|||.|:|.|:.|||..||..||..|:.::.|
pombe   322 -------GNEGKRMALIQQLLALTPEQINALPPAQRDQILSIRRQ 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	46/198 (23%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	40/175 (23%)
		CSTF2_hinge	112..190	CDD:291025	20/77 (26%)
		CSTF_C	377..416	CDD:291002	14/35 (40%)
ctf1	NP_596669.1	RRM_CSTF2_RNA15_like	9..83	CDD:240844	40/73 (55%)
		CSTF2_hinge	208..281	CDD:291025	24/112 (21%)
		CSTF_C	329..359	CDD:291002	14/29 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001914
OrthoInspector	1	1.000	-	-		otm47088
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	LDO	PTHR45735
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2262
SonicParanoid	1	1.000	-	-		X1629
TreeFam	0	0.000	Not matched by this tool.
	7	6.930