Protein Alignment CstF64 and CSTF2T

DIOPT Version :10

• Sequence 1: NP_477453.1
• Gene: CstF64 / 42239
• FlyBaseID: FBgn0027841
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_056050.1
• Gene: CSTF2T / 23283
• HGNCID: 17086
• Length: 616
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 53/254 - (20%)
• Similarity: 87/254 - (34%)
• Gaps: 92/254 - (36%)

  Fly     5 GGETSTKQQQELKAQIKIGHY--ILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVV 67
            ||.|.|  ..|.....:.|.|  ||.||:|||           .:::.||            |:|
Human   215 GGVTRT--TNEAIVLCEGGGYDIILIETVGVG-----------QSEFAVA------------DMV 254

  Fly    68 GKIRREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAE-------- 124
                                         |:|:::...:||:....| |.|.::.|:
Human   255 -----------------------------DMFVLLLPPAGGDELQGI-KRGIIEMADLVVITKSD 289

  Fly   125 ------ARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSC 183
                  |||...:.:|.:....|...|.|   |:.:.:..::...|.:.        .|.:|
Human   290 GDLIVPARRIQAEYVSALKLLRRRSEVWR---PKVIRISARSGEGITEM--------WDTMR--- 340

  Fly   184 GSPNYAAPEVISGKLYAGPEVD--VWSCGVILYALL--CGTLPFDDEHVPSLFRKIKSG 238
               .:....:.||:|.|..:..  ||...:|...:|  ..|.|...|.:|.:.||:.||
Human   341 ---EFQHQMLASGELAAKRQTQHKVWMWNLIQENVLEHFKTHPSIREQIPLMERKVLSG 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM_CSTF2_CSTF2T	10..94	CDD:410072	15/85 (18%)
		CSTF2_hinge	111..190	CDD:433869	15/92 (16%)
		CSTF_C	377..416	CDD:464130
CSTF2T	NP_056050.1	RRM_CSTF2_CSTF2T	10..94	CDD:410072
		CSTF2_hinge	112..191	CDD:433869
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..241		10/27 (37%)
		PRK12323	<242..>387	CDD:481241	37/214 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..418		33/153 (22%)
		9 X 5 AA tandem repeats of M-E-T-R-[AG]	418..462
		9 X 5 AA tandem repeats of G-[AT]-G-[MI]-Q	505..549
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..573
		CSTF_C	572..612	CDD:464130