DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CstF64 and rsp-2

DIOPT Version :9

Sequence 1:	NP_477453.1	Gene:	CstF64 / 42239	FlyBaseID:	FBgn0027841	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_496441.1	Gene:	rsp-2 / 174747	WormBaseID:	WBGene00004699	Length:	281	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	67/350 - (19%)
Similarity:	116/350 - (33%)	Gaps:	105/350 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 MRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNG 79
            |..|::|.:|..|::..::..|...|.:..:.:        ..||||.:::||..|..|:.:|||
Worm     1 MVRVYIGRLPNRASDRDVEHFFRGYGKLSDVIM--------KNGFGFVDFQDQRDADDAVHDLNG 57

  Fly    80 YEIGGRTLRVDNACTEKSRMEMQQLLQG----------------------PQVENPYGEPCEPED 122
            .|:          |.|:..:|..:...|                      .|..|.|..||...
Worm    58 KEL----------CGERVILEFPRRKVGYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTR- 111

  Fly   123 APELITKTVASLPPEQMYELMKQ--MKLCIVSNPSEARQMLMLNPQLAYALLQAMVVMRIVDP-Q 184
                ....:.:|.....::.:|.  .||.|....|||.:.         .:.||:|.....|. :
Worm   112 ----FRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKR---------NVNQAIVCFTSHDDLR 163

  Fly   185 QALGMLFKANQMPPVLGGNPHQGP---GNHTMMGQQQVPQQQVQIPQQQQQAPQPPMPVPGPGFP 246
            .|:..|               ||.   |.......:...:.:.:.|:::.::..|......|.
Worm   164 DAMNKL---------------QGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPA-- 211

  Fly   247 ANVHPNDIDLRMVPGGPMPMDPRMMGRGMDQDLRASLPNPVPPPLMDPRARAQMPPQQQQG---- 307
                                  |....|.|:..|.| .:..|....|.|||::...:.:.|
Worm   212 ----------------------RRRSPGSDRSDRKS-RSASPKKRSDKRARSESKSRSRSGGRRS 253

  Fly   308 VPQAPPAPYPSDPRQRPMDPRLRAG 332
            ...:||...|| |::|..:...|:|
Worm   254 RSNSPPNRSPS-PKKRRDNSSPRSG 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	24/118 (20%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	18/73 (25%)
		CSTF2_hinge	112..190	CDD:291025	17/80 (21%)
		CSTF_C	377..416	CDD:291002
rsp-2	NP_496441.1	RRM_SF	112..184	CDD:302621	17/95 (18%)
rsp-2	NP_496441.1	RRM1_SRSF4_like	3..71	CDD:240783	21/85 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810