Protein Alignment CstF64 and Cstf2

DIOPT Version :9

• Sequence 1: NP_477453.1
• Gene: CstF64 / 42239
• FlyBaseID: FBgn0027841
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001345982.1
• Gene: Cstf2 / 108062
• MGIID: 1343054
• Length: 603
• Species: Mus musculus
• Alignment Length: 604
• Identity: 240/604 - (39%)
• Similarity: 290/604 - (48%)
• Gaps: 191/604 - (31%)

  Fly     1 MADKAQEQSIMDKSMRSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYK 65
            ||........:|:|:|||||||||||||||:||:||||||||:|.:||:|||:|||||:|||||:
Mouse     1 MAGLPVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQ 65

  Fly    66 DQETALSAMRNLNGYEIGGRTLRVDNACTEKSRMEMQQLLQG-PQVENPYGEPCEPEDAPELITK 129
            ||||||||||||||.|..||.||||||.:||::.|::.|..| |.:|:||||...||||||.|:|
Mouse    66 DQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGESISPEDAPESISK 130

  Fly   130 TVASLPPEQMYELMKQMKLCIVSNPSEARQMLMLNPQLAYALLQAMVVMRIVDPQQALGMLFKAN 194
            .|||||||||:|||||||||:.::|.|||.||:.|||||||||||.||||||||:.||.:|.:..
Mouse   131 AVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQT 195

  Fly   195 QMPPVLGGNPH----QGPGN--HTMMGQQ--QVPQQQ------VQIPQQQQQAPQP---PMPV-- 240
            .:|.::.|||.    .|||:  :..|.||  |.||.|      |.......||..|   |.||
Mouse   196 NIPTLISGNPQPVHVAGPGSGPNVSMNQQNPQAPQAQSLGGMHVNGAPPMMQASMPGGVPAPVQM 260

  Fly   241 ------PGPGFPANVHPNDIDLRMVPGGPMPMD-------------------PRMMGR------- 273
                  ||||..|........:.|...||:||:                   .|:.|:
Mouse   261 AAAVGGPGPGSLAPAGVMQAQVGMQGAGPVPMERGQGTLQHSPVGPAGPASIERVQGQRTWMIWA 325

  Fly   274 -------------GMDQDLRASLPN---------------------PVPPPLMDP--------RA 296
                         |:|.......||                     |.|||...|        ..
Mouse   326 SVRGSTPSLLVSGGLDGIAVCDAPNDPRGGTLMTVTGDVEPRAYLGPPPPPHQGPPMHHVPGHEG 390

  Fly   297 RAQMPPQQQQGVPQAPPAPYPSDPR-----QR--PMDPR-------------------------- 328
            |.. ||...:|.|.|.|.|..::||     ||  |:|.|
Mouse   391 RGP-PPHDMRGGPLAEPRPLMAEPRGPMLDQRGPPLDARGGRDPRGLDARGMEARAMEARGLDAR 454

  Fly   329 ----------------------------LRA---------GPGPQQQAP-PQGIPQAPPPTQQ-- 353
                                        .||         ||.|..:.| |.|| |.|.|...
Mouse   455 GLEARAMEARAMEARAMEARAMEARAMEARAMEARGMDTRGPVPGPRGPMPSGI-QGPNPMNMGA 518

  Fly   354 ----------------QQAAAQQLQSRLGAHGVLPSDA----SDQEKAALIMQVLQLSDEQIAQL 398
                            .|.|:.|..|:.|  |..|..:    .|.||||||||||||:.:|||.|
Mouse   519 VVPQGSRQVPVMQGAGMQGASMQGGSQPG--GFSPGQSQVTPQDHEKAALIMQVLQLTADQIAML 581

  Fly   399 PSEQRVSIVMLKEQIAKST 417
            |.|||.||::|||||.|||
Mouse   582 PPEQRQSILILKEQIQKST 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM	<13..>112	CDD:223796	71/99 (72%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	60/73 (82%)
		CSTF2_hinge	112..190	CDD:291025	57/77 (74%)
		CSTF_C	377..416	CDD:291002	28/38 (74%)
Cstf2	NP_001345982.1	RRM	<7..332	CDD:330708	164/324 (51%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	60/73 (82%)
		CSTF2_hinge	113..191	CDD:316816	57/77 (74%)
		Rnc	<418..>475	CDD:330804	5/56 (9%)
		CSTF_C	559..599	CDD:316795	28/39 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838639
Domainoid	1	1.000	125	1.000	Domainoid score	I5446
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2630
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1455080at2759
OrthoFinder	1	1.000	-	-		FOG0001914
OrthoInspector	1	1.000	-	-		otm42761
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	LDO	PTHR45735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2262
SonicParanoid	1	1.000	-	-		X1629
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790