Protein Alignment CstF64 and RBM7

DIOPT Version :10

• Sequence 1: NP_477453.1
• Gene: CstF64 / 42239
• FlyBaseID: FBgn0027841
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 56/222 - (25%)
• Similarity: 94/222 - (42%)
• Gaps: 41/222 - (18%)

  Fly    16 RSVFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGY 80
            |::||||:..:.|||.|.|:|.:.|||:.:|:..|:: ||||.|.|..:|.:.:...||..|||.
Human    10 RTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKD-GKPKQFAFVNFKHEVSVPYAMNLLNGI 73

  Fly    81 EIGGRTLRVDNACTEKSRMEMQQLLQG----PQ-VENPYGEPCEPEDAPELITKTVASLPPEQMY 140
            ::.||.:::             |...|    || |...|.:......:|       .|..|...|
Human    74 KLYGRPIKI-------------QFRSGSSHAPQDVSLSYPQHHVGNSSP-------TSTSPSSRY 118

  Fly   141 E-LMKQMKLCIVSNPSEARQMLMLNPQLAYALLQAMVVMRIVDPQQALGMLFKANQM-----PPV 199
            | .|..|     ::.::..|....:|:    ..|...||.....|.:.|..|.::.:     .|.
Human   119 ERTMDNM-----TSSAQIIQRSFSSPE----NFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPS 174

  Fly   200 LGGNPHQGPGNHTMMGQQQVPQQQVQI 226
            :..:.|....:.:...:|..|..|.::
Human   175 VQSHSHSFNQSSSSQWRQGTPSSQRKV 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CstF64	NP_477453.1	RRM_CSTF2_CSTF2T	10..94	CDD:410072	30/77 (39%)
		CSTF2_hinge	111..190	CDD:433869	15/79 (19%)
		CSTF_C	377..416	CDD:464130
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	30/86 (35%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		3/9 (33%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		5/39 (13%)