DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31224 and ZBTB44

DIOPT Version :9

Sequence 1:NP_001287396.1 Gene:CG31224 / 42237 FlyBaseID:FBgn0051224 Length:1784 Species:Drosophila melanogaster
Sequence 2:NP_001357148.1 Gene:ZBTB44 / 29068 HGNCID:25001 Length:616 Species:Homo sapiens


Alignment Length:619 Identity:122/619 - (19%)
Similarity:209/619 - (33%) Gaps:208/619 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly  1044 GAESGTVTPSNQSQDVVSH-----------------QPTNFNAALAAVDCCS---------VALD 1082
            |.::.|.:.|:.||:::..                 |...|.|....:..||         .|.|
Human     2 GVKTFTHSSSSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAED 66

  Fly  1083 EDAKYLDLD-------------------ACKREQ----LSSSSNLPSASASTTSSSFAGAGTESS 1124
            |:...|||.                   :...|.    |:::|.:...|.::|.|.|    .:||
Human    67 ENKNVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEF----MKSS 127

  Fly  1125 LVGGLNIRTDEKMPAKGEISEQE--SNCDIENSWSESVYGDISQRYFRNQFSGGYHPDWRQDYYP 1187
            ::.    .|....|.||..:.||  |||:.     .|..|.||                      
Human   128 ILW----NTPNSQPEKGLDAGQENNSNCNF-----TSRDGSIS---------------------- 161

  Fly  1188 AQDLSAQ----------LREHKRFDFNAVDDEASSSSRRSHLTDLPTAATSSACTSSAMLAGPPI 1242
              .:|::          .||.:|             .|:|::...|.:.......:|:    |.:
Human   162 --PVSSECSVVERTIPVCRESRR-------------KRKSYIVMSPESPVKCGTQTSS----PQV 207

  Fly  1243 ASTSRAAAEAAAEA--AALA---------QRKPQRRKLYKCPHCEAIFEKLKE----RNAHMIGE 1292
            .::|.:.:|...:.  ::||         .|:.|.             ||:|:    |...:.|.
Human   208 LNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQP-------------EKVKQAENTRTLELPGP 259

  Fly  1293 HNYVRQNRRLICTQPQINTSMLTLQQQMIVQ-----SGEVEDSKDGIVKIKQEQCQEKQDV---E 1349
            ....|:....:..:....|..|..::.:.|:     ..||.:.....|...|....::|.|   |
Human   260 SETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSE 324

  Fly  1350 QMHDHSELLADVKDSELMGIGGDGDGDVDDDIKPPNQLDEKPTLPPLAMTTP-------AAKLAA 1407
            |:.:  :||...:.|.:        |.||:.:.     :..|||...:.|..       ...:..
Human   325 QVQE--DLLISPQSSSI--------GSVDEGVS-----EGLPTLQSTSSTNAPPDDDDRLENVQY 374

  Fly  1408 LYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKK 1472
            .|::.||.:.|.                           |:.||     .:..:.|.:|.|||.:
Human   375 PYQLYIAPSTSS---------------------------TERPS-----PNGPDRPFQCPTCGVR 407

  Fly  1473 FYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQ 1537
            |.|.:|...|:..|.|.|.|.|..|.|||....:|..|...|.|:...:|:||...|..:... :
Human   408 FTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEY-K 471

  Fly  1538 HRKRHTKMMVRK-KEYVCH-CGEVLPSKARFLWH 1569
            |..|.::.::|| :.|.|. ||.:..:....:.|
Human   472 HHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVH 505

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31224NP_001287396.1 C2H2 Zn finger 1466..1486 CDD:275368 8/19 (42%)
C2H2 Zn finger 1494..1514 CDD:275368 7/19 (37%)
zf-H2C2_2 1506..1531 CDD:290200 8/24 (33%)
C2H2 Zn finger 1522..1542 CDD:275368 5/19 (26%)
PHA00733 1527..1623 CDD:177301 10/45 (22%)
C2H2 Zn finger 1554..1573 CDD:275370 4/17 (24%)
C2H2 Zn finger 1580..1599 CDD:275368
C2H2 Zn finger 1613..1632 CDD:275368
COG5048 <1637..1780 CDD:227381
C2H2 Zn finger 1640..1660 CDD:275368
C2H2 Zn finger 1670..1690 CDD:275368
C2H2 Zn finger 1698..1718 CDD:275368
zf-H2C2_2 1710..1735 CDD:290200
C2H2 Zn finger 1726..1746 CDD:275368
zf-H2C2_2 1738..1763 CDD:290200
C2H2 Zn finger 1754..1774 CDD:275368
ZBTB44NP_001357148.1 BTB_POZ_ZBTB44 15..130 CDD:349537 21/118 (18%)
COG5048 383..>449 CDD:227381 24/97 (25%)
C2H2 Zn finger 401..421 CDD:275368 8/19 (42%)
zf-H2C2_2 413..438 CDD:338759 11/24 (46%)
C2H2 Zn finger 429..449 CDD:275368 7/19 (37%)
C2H2 Zn finger 457..476 CDD:275368 5/19 (26%)
zf-C2H2 487..508 CDD:333835 5/19 (26%)
C2H2 Zn finger 489..511 CDD:275371 4/17 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24383
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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