Protein Alignment CG31224 and Fiz1

DIOPT Version :10

• Sequence 1: NP_732361.1
• Gene: CG31224 / 42237
• FlyBaseID: FBgn0051224
• Length: 1784
• Species: Drosophila melanogaster
• Sequence 2: NP_035943.3
• Gene: Fiz1 / 23877
• MGIID: 1344336
• Length: 500
• Species: Mus musculus
• Alignment Length: 533
• Identity: 116/533 - (21%)
• Similarity: 168/533 - (31%)
• Gaps: 184/533 - (34%)

  Fly  1391 PTLP-PLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKL 1454
            |.:| |:|...||....|   ..:.::.|:.|:.....|:|.:
Mouse     7 PVVPAPIAAPGPAPSATA---PRVPFHCSECGKSFRYRSDLRR---------------------- 46

  Fly  1455 YDAHLTEH----PAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHT 1515
               |...|    |..|..|||.|....|.:.||:.|.|.:.:.|..|.|.|...:.|:.|..:||
Mouse    47 ---HFARHTALKPHACPRCGKGFKHSFNLANHLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHT 108

  Fly  1516 GQTPLKCKICGKKFKRYSNLTQHRKR-HTKMMVRKKE------------YVCHC----------- 1556
            |:.|..|.:|..:|...|:|.:|.|| |...:....:            .|| |
Mouse   109 GEKPYCCLVCELRFSSRSSLGRHLKRQHRGTLPSPLQPSPGLPPLSSPCSVC-CNVGPCSVCGGG 172

  Fly  1557 ----GEVLPSKARFLW------HKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPM 1611
                ||.|.......|      ......|.|..|..|..||.|...|..| ..||:|    .:|.
Mouse   173 GSSGGEGLEGAGATSWGLAEAAAAAAASLPPFACGACARRFDHGRELAAH-WAAHTD----VKPF 232

  Fly  1612 ECPMCKQIF-AKTSIKAHMATHSTE---------------PQYDCAICSKSFSTKWNLKIHSW-- 1658
            :||.|::.| |...::.|..||..:               |:    :..:..:::......:|
Mouse   233 KCPRCERDFNAPALLERHKLTHDLQGSNAPPTQVWASGGGPE----VAGEGDASEVGAAPQTWDA 293

  Fly  1659 ---------------------------------VHANRTAKPFKCEYCPKAFVRELDFKNHINAH 1690
                                             ..|:.....::|: |...|.......:|:.||
Mouse   294 GLLLSPTGAGVPKLEALLPGDEGSGNDQAPAAAAEASSEDTLYQCD-CGTFFASAPALASHLEAH 357

  Fly  1691 KQIKPYTCEYCGCKFIRKYNYMRHRREHH------------------------------------ 1719
            .....|.|.:||..:........|||..|
Mouse   358 SGPATYGCGHCGALYAALAALEEHRRASHGEGSGEAAPDGEGNQAAGGPGPGSSSRSKKIFGCSE 422

  Fly  1720 -------------------GTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKT 1765
                               |.|.|.|.:|.|.|....||..||.:|..||||.|.||||...|.:
Mouse   423 CEKLFRSPRDLERHVLVHTGEKPFPCLECGKFFRHECYLKRHRLLHGTERPFPCHICGKGFITLS 487

  Fly  1766 NHNKHLKIHHSRD 1778
            |.::|||:|...|
Mouse   488 NLSRHLKLHRGMD 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31224	NP_732361.1	C2H2 Zn finger	1466..1486	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1494..1514	CDD:275368	6/19 (32%)
		zf-H2C2_2	1506..1531	CDD:463886	9/24 (38%)
		C2H2 Zn finger	1522..1542	CDD:275368	8/20 (40%)
		PHA00733	1527..1623	CDD:177301	32/130 (25%)
		C2H2 Zn finger	1554..1573	CDD:275370	6/39 (15%)
		C2H2 Zn finger	1580..1599	CDD:275368	7/18 (39%)
		C2H2 Zn finger	1613..1632	CDD:275368	6/19 (32%)
		COG5048	<1637..1780	CDD:227381	44/232 (19%)
		C2H2 Zn finger	1640..1660	CDD:275368	1/54 (2%)
		C2H2 Zn finger	1670..1690	CDD:275368	4/19 (21%)
		C2H2 Zn finger	1698..1718	CDD:275368	6/19 (32%)
		zf-H2C2_2	1710..1733	CDD:463886	10/77 (13%)
		C2H2 Zn finger	1726..1746	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1754..1774	CDD:275368	10/19 (53%)
Fiz1	NP_035943.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		6/16 (38%)
		zf-C2H2	29..51	CDD:395048	5/46 (11%)
		C2H2 Zn finger	31..51	CDD:275368	5/44 (11%)
		zf-H2C2_2	43..68	CDD:463886	9/49 (18%)
		C2H2 Zn finger	59..79	CDD:275368	8/19 (42%)
		zf-H2C2_2	71..94	CDD:463886	8/22 (36%)
		C2H2 Zn finger	87..107	CDD:275368	6/19 (32%)
		C2H2 Zn finger	115..133	CDD:275368	6/17 (35%)
		C2H2 Zn finger	206..226	CDD:275370	7/20 (35%)
		C2H2 Zn finger	234..254	CDD:275370	6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..284		1/32 (3%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..328		0/21 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..415		2/31 (6%)
		C2H2 Zn finger	420..440	CDD:275368	0/19 (0%)
		zf-H2C2_2	432..457	CDD:463886	7/24 (29%)
		C2H2 Zn finger	448..468	CDD:275368	8/19 (42%)
		zf-C2H2	474..496	CDD:395048	11/21 (52%)
		C2H2 Zn finger	476..496	CDD:275368	10/19 (53%)