DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31224 and Y5F2A.4

DIOPT Version :9

Sequence 1:	NP_001287396.1	Gene:	CG31224 / 42237	FlyBaseID:	FBgn0051224	Length:	1784	Species:	Drosophila melanogaster
Sequence 2:	NP_502063.1	Gene:	Y5F2A.4 / 178004	WormBaseID:	WBGene00012385	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	299	Identity:	71/299 - (23%)
Similarity:	112/299 - (37%)	Gaps:	94/299 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1494 CYVCDKKFVVRSALVEH-MRMH----------TGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMV 1547
            |..|.|.|.::..|.:| :|||          :...||||.:|.|.|.|.|:|.:|:..|..:
Worm     6 CQDCGKTFDLKRYLTKHELRMHKNVVKSKNDRSASDPLKCSMCDKVFPRLSHLQRHQMTHLNV-- 68

  Fly  1548 RKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSD----KFDYA 1608
              :.|                          .|.:|.::||..:.|.||:...||:    :.|:.
Worm    69 --RNY--------------------------SCTFCEEKFVQKSHLTRHVSRKHSNAPGVEVDWT 105

  Fly  1609 EPMECPMCKQIFAKT-SIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEY 1672
               .|..|.|:|..| .::.|..|:.                    ::|            ||:.
Worm   106 ---ACDKCGQLFKTTYEMRIHRQTYH--------------------ELH------------KCKQ 135

  Fly  1673 CPKAFVRELD-FKNHINAHKQIKPYT--CEYCGCKFIRKYNYMRHRREHHGTKK--FTCDQCDKS 1732
            |.:......| .:.|   |.|.:.|:  |:.||..|.|..:.:.|  |....||  |.|..||..
Worm   136 CQEVIEAGSDGLRKH---HMQCRKYSNVCDECGASFSRPADLVSH--ETSCLKKFAFVCKPCDSY 195

  Fly  1733 FHRHYYLIEH-RRMHTGERPFTCTICGKSSTTKTNHNKH 1770
            |.:...|..| ::.|.  .|..|:.|.:.|.|...:::|
Worm   196 FRQRVQLDRHIKKAHF--HPTKCSKCEQISDTPVQNSRH 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31224	NP_001287396.1	C2H2 Zn finger	1466..1486	CDD:275368
		C2H2 Zn finger	1494..1514	CDD:275368	7/20 (35%)
		zf-H2C2_2	1506..1531	CDD:290200	12/35 (34%)
		C2H2 Zn finger	1522..1542	CDD:275368	8/19 (42%)
		PHA00733	1527..1623	CDD:177301	22/99 (22%)
		C2H2 Zn finger	1554..1573	CDD:275370	0/18 (0%)
		C2H2 Zn finger	1580..1599	CDD:275368	7/18 (39%)
		C2H2 Zn finger	1613..1632	CDD:275368	6/19 (32%)
		COG5048	<1637..1780	CDD:227381	32/140 (23%)
		C2H2 Zn finger	1640..1660	CDD:275368	1/19 (5%)
		C2H2 Zn finger	1670..1690	CDD:275368	4/20 (20%)
		C2H2 Zn finger	1698..1718	CDD:275368	6/19 (32%)
		zf-H2C2_2	1710..1735	CDD:290200	9/26 (35%)
		C2H2 Zn finger	1726..1746	CDD:275368	6/20 (30%)
		zf-H2C2_2	1738..1763	CDD:290200	7/25 (28%)
		C2H2 Zn finger	1754..1774	CDD:275368	5/17 (29%)
Y5F2A.4	NP_502063.1	C2H2 Zn finger	6..27	CDD:275368	7/20 (35%)
		zf-C2H2	44..65	CDD:278523	9/20 (45%)
		C2H2 Zn finger	45..65	CDD:275368	8/19 (42%)
		C2H2 Zn finger	73..94	CDD:275368	7/20 (35%)
		C2H2 Zn finger	107..126	CDD:275368	6/18 (33%)
		C2H2 Zn finger	161..181	CDD:275368	7/21 (33%)
		C2H2 Zn finger	189..212	CDD:275368	7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I3725
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050