DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31224 and ZNF579

DIOPT Version :9

Sequence 1:NP_001287396.1 Gene:CG31224 / 42237 FlyBaseID:FBgn0051224 Length:1784 Species:Drosophila melanogaster
Sequence 2:XP_016881898.1 Gene:ZNF579 / 163033 HGNCID:26646 Length:640 Species:Homo sapiens


Alignment Length:418 Identity:90/418 - (21%)
Similarity:126/418 - (30%) Gaps:132/418 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1463 PAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGK 1527
            |..|.|||:.|......|.|...|.|.:...|.:|.|.|...:.|..|:|.|..|.||:|..|.:
Human    43 PLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAACPR 107

  Fly  1528 KFKRYSNLTQHRKRHTKMMVRKKEYVCHCG--------EVLPSKARFLWHKETHDLKPKCCPYCC 1584
            .|...:.|.:|..:.            |.|        .|....|...|..:....:|...    
Human   108 TFPEPAQLRRHLAQE------------HAGGEVELAIERVAKETAEPSWGPQDEGSEPPTT---- 156

  Fly  1585 DRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEP------------- 1636
               ..|.:.......|..:.:...||      ..:.|.||......:.|.|.             
Human   157 ---AAAGATEEEAVAAWPETWPAGEP------STLAAPTSAAEPRESESEEAEAGAAELRAELAL 212

  Fly  1637 ------------QYD----CAICSKSFSTKWNLKIHSWVHAN----------RTAKPFKCEYCPK 1675
                        |.|    |..|.::|:||..||.|..:...          ...|..:|..|.|
Human   213 AAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICLK 277

  Fly  1676 AFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMR-HRREH--------------------- 1718
            ||.|......|...|...:|:.|..||..| |..:|:| |||.|                     
Human   278 AFARPWSLSRHRLVHSTDRPFVCPDCGLAF-RLASYLRQHRRVHGPLSLLAPLPAAGKKDDKASG 341

  Fly  1719 -------------------------------------HGTKKFTCDQCDKSFHRHYYLIEHRRMH 1746
                                                 .|..:|.|.:|.|.|.|..:|.:|...|
Human   342 ARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARPPAGEPRFWCPECGKGFRRRAHLRQHGVTH 406

  Fly  1747 TGERPFTCTICGKSSTTKTNHNKHLKIH 1774
            :|.|||.|..|.:......:..:|.::|
Human   407 SGARPFQCVRCQREFKRLADLARHAQVH 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31224NP_001287396.1 C2H2 Zn finger 1466..1486 CDD:275368 7/19 (37%)
C2H2 Zn finger 1494..1514 CDD:275368 7/19 (37%)
zf-H2C2_2 1506..1531 CDD:290200 10/24 (42%)
C2H2 Zn finger 1522..1542 CDD:275368 5/19 (26%)
PHA00733 1527..1623 CDD:177301 14/103 (14%)
C2H2 Zn finger 1554..1573 CDD:275370 5/26 (19%)
C2H2 Zn finger 1580..1599 CDD:275368 1/18 (6%)
C2H2 Zn finger 1613..1632 CDD:275368 3/18 (17%)
COG5048 <1637..1780 CDD:227381 49/211 (23%)
C2H2 Zn finger 1640..1660 CDD:275368 8/19 (42%)
C2H2 Zn finger 1670..1690 CDD:275368 7/19 (37%)
C2H2 Zn finger 1698..1718 CDD:275368 10/20 (50%)
zf-H2C2_2 1710..1735 CDD:290200 12/83 (14%)
C2H2 Zn finger 1726..1746 CDD:275368 7/19 (37%)
zf-H2C2_2 1738..1763 CDD:290200 9/24 (38%)
C2H2 Zn finger 1754..1774 CDD:275368 3/19 (16%)
ZNF579XP_016881898.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24383
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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