DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qin and LCL3

DIOPT Version :9

Sequence 1:	NP_650735.3	Gene:	qin / 42236	FlyBaseID:	FBgn0263974	Length:	1857	Species:	Drosophila melanogaster
Sequence 2:	NP_011430.1	Gene:	LCL3 / 852795	SGDID:	S000003053	Length:	274	Species:	Saccharomyces cerevisiae

Alignment Length:	270	Identity:	56/270 - (20%)
Similarity:	92/270 - (34%)	Gaps:	73/270 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   598 ALVSQKLTNENL-----YNVFLTDIGVHLHVRCSDFRVVPERI--SHLPYSAVHCSLSE------ 649
            |::|..||...|     |..:||..     .|.:|   :|.||  .|..|..| .|:.:
Yeast    15 AVLSIILTGSTLTLIYTYKRYLTQF-----KRTND---IPRRIFRKHWLYGKV-TSVGDGDNFHF 70

  Fly   650 -LMPKNGESEWDSKASAFLK---QIVQN-NPVRVIVKKALTYELHGVDLITSNYDTNISV---RD 706
             .||......|     .:|:   |:::| :....:|..:........:.||....|...:   :.
Yeast    71 FHMPGGIRGGW-----GWLRPVPQMIKNDSTAEKLVGDSRNMRFFNFNWITHGRSTKSKIQKAKS 130

  Fly   707 SFLYCGLAISRDGAPLWLPPAPTALRLPRISFRFGDVYMVQMLHVEDPQEFYVMRHDYEKKRLWL 771
            .||...:            |......||.|..|...:...:..|..:|.:.:     ..:..:||
Yeast   131 QFLKLNV------------PYKNRKNLPTIPIRLCGIDAPERAHFGNPAQPF-----GNEALIWL 178

  Fly   772 Q---FSLQEAMDRINISQLQNIFLGQLHLGCVLQSG-----GQWKRASIEQILPDGYVLVHLVDE 828
            |   ...:..:..::|.|...         ||.:..     |.||..|:| :|.||..:|:   |
Yeast   179 QNRILGKKVWVKPLSIDQYNR---------CVARVSYWDWFGGWKDLSLE-MLKDGLAVVY---E 230

  Fly   829 GPSQKVFWDQ 838
            |.....|.|:
Yeast   231 GKVNTEFDDR 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..75	CDD:291308
		BBOX	139..174	CDD:197662
		TUDOR	536..648	CDD:278965	17/56 (30%)
		TUDOR	741..859	CDD:278965	22/106 (21%)
		TUDOR	<805..839	CDD:119391	13/34 (38%)
		TUDOR	981..1107	CDD:278965
		TUDOR	1296..1403	CDD:278965
		TUDOR	1337..1385	CDD:119391
		TUDOR	1710..1761	CDD:119391
LCL3	NP_011430.1	SNase	149..261	CDD:395448	23/110 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900