Protein Alignment qin and tdrd5

DIOPT Version :10

• Sequence 1: NP_650735.3
• Gene: qin / 42236
• FlyBaseID: FBgn0263974
• Length: 1857
• Species: Drosophila melanogaster
• Sequence 2: XP_031756124.1
• Gene: tdrd5 / 780220
• XenbaseID: XB-GENE-5884032
• Length: 1010
• Species: Xenopus tropicalis
• Alignment Length: 1090
• Identity: 210/1090 - (19%)
• Similarity: 360/1090 - (33%)
• Gaps: 336/1090 - (30%)

  Fly    18 SNLQNLLRCPKCSKCFTYLYNTNS-----EEDNHR-PFLLGCGHTLCESCLWNDR--LDPKCAV- 73
            |.::.||..|...|..|.|..|..     :|...| ..|:.|....|.:...|.|  :.|:|.|
 Frog    98 STMELLLDMPSVVKIHTQLDGTVKLSAVVDETTRRIADLVSCQKDRCTARTRNRRRNIRPRCPVD 162

  Fly    74 -----CHSPAPPTIVAKRSDCKSVANLRDLYELNYHVLGRTSSLSYLLPFAKDSANQSLSPSSIS 133
                 ..||..|..|  :||      ||||.                          |:||..:|
 Frog   163 LVRRGRVSPVLPATV--KSD------LRDLL--------------------------SVSPLLLS 193

  Fly   134 EIVQTVKCSECGNA---TASGECRQCNAFY-----CRRCFDAVH-KRSRVLKSHIFRNSTEQDSS 189
            |:.:... |..|.:   |..|       ||     .|...|.|. |::|.....:.|||  :...
 Frog   194 ELEKAFS-SRFGRSFQYTRYG-------FYSMLEVLRSITDIVEVKQTRAGSLLVLRNS--ETGR 248

  Fly   190 FSKKLRVGDQYFTL-PSQNLCIHHRMPKD-----------------------KYCMKCYRSHCQI 230
            .|..|.|......: |.:..|:..:..|:                       |...|...|..:.
 Frog   249 ISASLCVKQSQLAIDPKKTSCVLEQCLKEPRTPEKKTSETVTYLKVSPPEPQKLSSKESPSVTRS 313

  Fly   231 CSTVHHSGHRIRKL---------IEINQSYASEIPTTLNSLNMAHIHVLNGKQVVQRAKQKLNDY 286
            .|.:.:|.::.::|         ::.|::.|..: |...|...:|..||:...|.       |..
 Frog   314 TSPLINSSNKEQRLKLNVLLDESLKSNENKAPPV-TNFTSAVPSHNSVLSNSLVG-------NSV 370

  Fly   287 ATETL-ASISKRFSHL---HGLLQVAELQVIEKLRESSLPPQLKLNEAMGQLSGYETVIERLTKS 347
            ::||| ..:|:..||:   |......:..|:|.| |..|..:|||..|
 Frog   371 SSETLFTKMSRPTSHVEADHSAASEPDASVLEWL-EKKLEKELKLCLA----------------- 417

  Fly   348 LNSGVGNDM--AVPRDVSLRWLLKLICEH-----LEKIPTTVQVSKVDENPYRVTCSRFMDISNI 405
             ..|.|..:  |:..|:.     .::.:|     :.::||..:.....:.|::
 Frog   418 -RKGAGGSVSDALRMDIQ-----HVVNQHSDGLKISQLPTVFKSFTGKDLPFK------------ 464

  Fly   406 FKCEFVNPNIQVCFKTDLEISRSLSSSPKGEITFLTSSSSSKE--NFDPHSRKLLLAQNSKLKKA 468
                      ::.|.:.:|:..||     |:|..:.|:...|:  .||...:.|:
 Frog   465 ----------ELGFISVMELVGSL-----GDILCVESTVDGKDWKLFDAKKKDLV---------- 504

  Fly   469 TQVSQSQKKRGKNATEVAQSSLNSTAAIIDEFPAKDLDFLHNFSSLD-------ITKRNKTTED- 525
                 .:...|..:|....||.||:.....  |.|.:..:  ||.:|       :..:..:||.
 Frog   505 -----DEFSAGLPSTSSILSSWNSSQQTTT--PVKPVGTI--FSKVDEKLWWGPLELKLCSTEQI 560

  Fly   526 --SSDWFKTDTL-------------VRVRSVQSPEDFYVQ--GIHAAQRLREELDTFAHTLSDSS 573
              ..|..:...|             |.|.:::||..|||:  |...:::|.:.:....|..|:..
 Frog   561 DIPPDAVRNQKLHCLPSMKRGFMIGVYVENIESPSQFYVRCCGKDTSEKLEDMMIEMRHCYSNEC 625

  Fly   574 SVPPTIV------VGQNYIIHHKDKDRYYRALVSQKLTNENLYNVFLTDIGVHLHVRCSDFRVVP 632
            .....||      |||.|.:.......:||.:| ..:.|..|.:||..|.|....|:.|..|.:.
 Frog   626 VSERYIVTDNCISVGQIYALRVPGDVWWYRVIV-HDIKNSELLDVFYPDFGNVATVKKSWLRFLK 689

  Fly   633 ERISHLPYSAVHCSLSELMPKNGESEWDSKASAFLKQIVQNNPVRVIVKKALTYELHGVDLITSN 697
            .....:|..||..||..:  .:.|.:|.::|....:|:....|:..:|.:.:...|| :.|..::
 Frog   690 NCYMKIPAQAVPSSLPYV--TSTEDQWSAQAIKKFQQLCSCIPLVGMVLQYVQDILH-IFLCDTS 751

  Fly   698 YDTNISVRDSFLYCGLA----------ISRDGAPL--WLPPAPTALRLPRISFRFGDVYMVQMLH 750
            .:.::.:....:..|||          ||:...|.  :|.|:.
 Frog   752 SEEDLYLHQLLISQGLAKMEPEHACKKISKKRNPFMQYLTPSQ---------------------- 794

  Fly   751 VEDPQEFYVMRHDYEKKRLWLQFSLQEAMDRINISQLQNIFLGQLHLGCVLQSGGQWKRASIEQI 815
             |.|||                          ..|||.           |.....|.:....:::
 Frog   795 -EQPQE--------------------------ESSQLS-----------VPSESSQSEIPCAKEV 821

  Fly   816 LPDGYVLVHLVDEGPSQKVFWDQLFVLPQKFWDTGLAIKCCLADVETRAEHSYTWTPEGTTLFKQ 880
            ..:..:.:..::..||....||:.:.......|...|......|.:.:.|:..:   :.|..||.
 Frog   822 KDEDDLGMPYLEAFPSGSDVWDENWAFSDGACDYDTAPTIPKVDTQKQQENKVS---QETQPFKF 883

  Fly   881 LTSNPRLYMDVISCTEDLVYVSLHFERSNSETTSV---------GVQLVAHGHCT---SSGESSR 933
            ...:..  ..|:....:..|:||...|.:.|:|.:         .|..::|...|   ..|.||.
 Frog   884 CIDSAD--ASVVHHPLEEFYISLIKSRKSQESTDIQQSPPTEEQHVAEISHRSATEQLQGGSSSS 946

  Fly   934 MITPTVSNRSVRFDEETKKFIAQQK-----------------VRPVELSP 966
            |:    ..:.:.:::|...:..|.|                 ..||.|.|
 Frog   947 ML----CEKKLYYEKEDLPYCQQSKCSFSPLLGFQRLQIPRSATPVALGP 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..76	CDD:434085	15/64 (23%)
		Bbox1	140..178	CDD:380815	11/46 (24%)
		Bbox2	208..244	CDD:380814	7/58 (12%)
		TUDOR	536..648	CDD:425754	33/119 (28%)
		TUDOR	742..859	CDD:425754	15/116 (13%)
		Tudor_SF	989..1139	CDD:470623
		TUDOR	1296..1403	CDD:425754
		TUDOR	<1703..1781	CDD:425754
tdrd5	XP_031756124.1	LOTUS_1_TDRD5	50..142	CDD:193599	12/43 (28%)
		LOTUS_2_TDRD5	174..242	CDD:193589	24/109 (22%)
		LOTUS_3_TDRD5	426..499	CDD:193590	16/104 (15%)
		Tudor_TDRD5	587..704	CDD:410490	31/117 (26%)