DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qin and F32E10.5

DIOPT Version :9

Sequence 1:	NP_650735.3	Gene:	qin / 42236	FlyBaseID:	FBgn0263974	Length:	1857	Species:	Drosophila melanogaster
Sequence 2:	NP_501230.1	Gene:	F32E10.5 / 177535	WormBaseID:	WBGene00017992	Length:	549	Species:	Caenorhabditis elegans

Alignment Length:	471	Identity:	89/471 - (18%)
Similarity:	162/471 - (34%)	Gaps:	128/471 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   961 PVELSP---YRMPDNTERNKRTTVNILYVRKPDEFYVTLPHFQKAINNLQKSVQKA----AAAMY 1018
            |::|.|   ||:.:::              .|.:..:....|.:...||.:.:|:.    .|.:|
Worm    69 PIDLYPCEYYRIVEHS--------------MPTDIGLQPKRFDRIKENLTEKLQQVFRHQDADLY 119

  Fly  1019 ---QNMLPRTDWQVGDMCYARVQANCDSQALWYRGVVTGVIPPGITCPIVRYQVHLRDLG----E 1076
               .:::|.....|   |.         |..||||.:..|.|.||.     ..|:|.|.|    .
Worm   120 MPENHLIPTVACAV---CI---------QGTWYRGKIENVPPRGIW-----MYVNLIDAGMSRQV 167

  Fly  1077 LIDDVHSSSLANIDEADMRISSSAKRCHLHGIRPIGDEWSKDAIDFFMDQLKAYNEIHVTGRGRT 1141
            :..||....||......|.:.::.:...:|       ...:..:|.|.:.::
Worm   168 MKSDVRRLPLAFGHYPPMVVKATIRGAVIH-------RMDRGKVDQFQNMIR------------- 212

  Fly  1142 ENSLSVILWGSLSILTGPFSPATI--KYVNINK-ALLMAGMAEKDHNSDSEDDQQSMPENVSV-N 1202
              ::..:....::..|.||.....  ||..:|. :.|:|             .::..|....| .
Worm   213 --NIDYLARCQITTCTEPFQIVLCHPKYEFMNMCSFLLA-------------PRRGQPSQEGVWI 262

  Fly  1203 SEEAAKANDWESCLSKIDGTSKTNDSLNLIESRSVTVGFEHNEDMPPLALLEDLGNTKNTTGETT 1267
            ..|.||..:.|:...:.|......||..|.:......|:::.|.       :|....:     :.
Worm   263 PREIAKQLERENGFERNDYDDSGADSDFLEDEEEEDAGWDYGEG-------DDYAYLR-----SF 315

  Fly  1268 PPAGWTTRRKCDKSVFTAIATNVTYECCIYLTLASDKPFIEHMGNLLVREYKPLMDKQKERSTSY 1332
            |||....|...|:.:...|..    |..||||   .|..:|..     ||.:..:.|:||...|.
Worm   316 PPACKIFRMSEDEFMVERIEN----ERIIYLT---SKDMLERR-----REAEEYLTKEKESLESL 368

  Fly  1333 TYKVGQAVVVTYHMD-NMIYRGIVQRLE---NNHNEYTVYYVDYG-NMELVKAD----------E 1382
                 ..|.:.|... ::.::|.::|..   ...:...:..:||| ::|:.|:|          .
Worm   369 -----PDVWMAYGTSCSVFHQGTMKRASCCGEEGSTIQLLLIDYGISIEVSKSDVYNIPNKDEVN 428

  Fly  1383 MLPYAPFPDLNAMCFL 1398
            |.|:.....:.:..|:
Worm   429 MEPFVTLVSIKSFPFI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..75	CDD:291308
		BBOX	139..174	CDD:197662
		TUDOR	536..648	CDD:278965
		TUDOR	741..859	CDD:278965
		TUDOR	<805..839	CDD:119391
		TUDOR	981..1107	CDD:278965	28/136 (21%)
		TUDOR	1296..1403	CDD:278965	25/118 (21%)
		TUDOR	1337..1385	CDD:119391	11/62 (18%)
		TUDOR	1710..1761	CDD:119391
F32E10.5	NP_501230.1	TUDOR	68..193	CDD:278965	33/154 (21%)
		TUDOR	128..179	CDD:197660	18/67 (27%)
		TUDOR	371..424	CDD:197660	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D117171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010