Protein Alignment qin and tsn-1

DIOPT Version :10

• Sequence 1: NP_650735.3
• Gene: qin / 42236
• FlyBaseID: FBgn0263974
• Length: 1857
• Species: Drosophila melanogaster
• Sequence 2: NP_494839.1
• Gene: tsn-1 / 173811
• WormBaseID: WBGene00006626
• Length: 914
• Species: Caenorhabditis elegans
• Alignment Length: 939
• Identity: 169/939 - (17%)
• Similarity: 305/939 - (32%)
• Gaps: 316/939 - (33%)

  Fly  1072 RDLGELIDDVHSSSLANIDEADM-RISSSAKRCHLHGIR--PIGDEWSKDAIDFFMDQLKAYNEI 1133
            ||.|.:.       |.....||. .::..|....|..:|  .:.||:|...:: ..:|.|:
 Worm   108 RDHGRIY-------LGGTSPADAENVAEGAVSAGLLEVRQGKVADEYSTKLLE-LQEQAKS---- 160

  Fly  1134 HVTGRGRTENSLSV---ILWGSLSILTGP---------------------------FSPATIKYV 1168
              .|||:..::...   |.|    ::..|                           |.....:|:
 Worm   161 --AGRGKWNSNAGTIRDIRW----VIDNPRELVDKYAQKPIDAVIEMVRDGSTVRAFLLPNFEYI 219

  Fly  1169 NINKALLMAGMAEKDHNSDS------------------EDDQQSMPENVS----VNSEEAAKAND 1211
            .:..:.:.|......:.:||                  :.|.|.:.|:.|    |.|....|.|.
 Worm   220 TLQLSGVRAPSTRNPNAADSRAEAFSEEAKFFAESRLLQRDVQIILESTSNQNFVGSIVHPKGNI 284

  Fly  1212 WESCLSKIDGTSKTND-SLNLIESRSVTVGFEHNEDMPPLALLEDLGNTKNTTGETTPPAGWTTR 1275
            .||.|.  :|.:|..| |:.|     .|.|.:...|....|..:.|...|:....::..:|
 Worm   285 AESLLR--EGYAKCVDWSIGL-----CTGGAQKLRDAERQAKEKRLRLWKSYQPTSSAYSG---- 338

  Fly  1276 RKCDKSVFTAIATNVTYECCIYLTLASDKPFIEHMGNLLV--------------REYKPLMD--- 1323
               |:..||.....:.....:.:..........|:.::.:              |:::||.|
 Worm   339 ---DRKAFTGKVVEIVLSDAVVVQKDDGSEVKLHLSSIRLPRESGDDKATGGPGRQFRPLYDIPF 400

  Fly  1324 --KQKE--------------------------RSTSYTYKVGQAVVVTYHMDNMIYRGIVQRL-- 1358
              :.:|                          ..|..|.|:|...:.    :.:|.||:.:.:
 Worm   401 MFQAREFLRKRLLGKKVQIQIDYVQPKSENFPEKTCATIKIGDQNIA----EGLISRGLSKVVRH 461

  Fly  1359 ----ENNHNEYTVYYVDYGNMELVKADEMLPYAPFPDLNAMCFLVELHGVRSKQGKYSLKEMDTV 1419
                ||..:||               |.:|             ..|.:..:.|:|.::.|..:..
 Worm   462 RADDENRSSEY---------------DTLL-------------AAEANAEKGKKGLFADKTAEKK 498

  Fly  1420 HLNLVMKLSGVRIVDDETVGPNKIPKCQIKVGNVDIATMMIDSGMSVPIEKQTIKNNTKYLPSQK 1484
            ..:.:.:::|     |.......:|..| :.|..:.....:..|..:.|          |:|.:.
 Worm   499 DTHRIQEITG-----DLAKAKQFLPYLQ-RGGRAEGVVEFLSGGSRLRI----------YIPKET 547

  Fly  1485 FLEDFKV--FDELDHLAAGEGELSDKEAPPTQRKHDSISSVQQPPTKKFLVDQEEVEAFECDQDF 1547
            .|..|.:  .:.......|.|.:|...|.|..   |..::.    |:| ||.|.||
 Worm   548 VLITFLLGGINCPKGARVGPGGVSTGAAEPFA---DEAAAF----TRK-LVLQHEV--------- 595

  Fly  1548 DCQQAAQKMHLNNNFYLGDFGKYADETTAR-------------------DEDEPH-------SNS 1586
              |...:....|.|| :|......|..|:|                   .|...|       .|.
 Worm   596 --QLEVESTDKNGNF-VGYLYVSPDGNTSRAINLSEALVENGLASLHFTAERSGHYNALLSAENK 657

  Fly  1587 SKSIDMEVFANVNDSQLEPLNSFATEQLIRRIALRQQEIKDSITFSPIDTSSVRSFYDASASFKT 1651
            :|.....::||..:.|                  .|:|::    ....|||      :...:|:.
 Worm   658 AKKAKKNIWANFTEEQ------------------HQEEVE----VQQADTS------ERKQNFRQ 694

  Fly  1652 LSLPNGVKEFYCTVDNVLSDTELQIAPCLSEFTKHEIS---LIQETSTLIKDA----EPL---ME 1706
            :::.:                   |||....|:...|.   .|::.:|.::.|    .||   ..
 Worm   695 VAVTD-------------------IAPGALRFSAQNIEDGPKIEKMTTEMRQALAEHPPLAGSYT 740

  Fly  1707 PKVGDLCLARYSRDKQWYRANIKEISPILSPTSEQVTVFYIDFHDTEKVSFNHLKVMPSQLFMFP 1771
            .|.||||:|::|:|.||||..::.:      .:.|..:.|||:.:.|.:....|..:|:....||
 Worm   741 TKRGDLCVAKFSQDGQWYRCKVESV------RAGQAEIVYIDYGNRETIEAVKLAQIPAGFANFP 799

  Fly  1772 --LRSFCVKLHGIKRNKSFKEKSVRQALQACLCQHPLVFARVHYPLN-------YYPN---RPNC 1824
              :|.:.:.|..:. |:.:.:.: ..|....|..|..||....|.:.       ||.:   :.:.
 Worm   800 AGVREYNLALAKLP-NEDYVQLT-SDAFAQYLFGHSSVFINSEYKVGTSEYVTVYYDSGNKKVDI 862

  Fly  1825 DADLIE--VELYENRHEKKLVYQSLCENW 1851
            ...||.  :.|.::|.|.:|  |:|..::
 Worm   863 GKSLIAEGLALADHRREPRL--QTLVNDY 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..76	CDD:434085
		Bbox1	140..178	CDD:380815
		Bbox2	208..244	CDD:380814
		TUDOR	536..648	CDD:425754
		TUDOR	742..859	CDD:425754
		Tudor_SF	989..1139	CDD:470623	15/69 (22%)
		TUDOR	1296..1403	CDD:425754	20/157 (13%)
		TUDOR	<1703..1781	CDD:425754	25/82 (30%)
tsn-1	NP_494839.1	SNc	22..168	CDD:214615	17/73 (23%)
		SNc	193..328	CDD:214615	26/141 (18%)
		SNc	341..492	CDD:214615	24/182 (13%)
		SNc	524..668	CDD:214615	32/173 (18%)
		Tudor_TDRD11	714..796	CDD:410504	24/87 (28%)
		SNc	758..904	CDD:469627	30/142 (21%)