DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment qin and ZK1240.1

DIOPT Version :9

Sequence 1:	NP_650735.3	Gene:	qin / 42236	FlyBaseID:	FBgn0263974	Length:	1857	Species:	Drosophila melanogaster
Sequence 2:	NP_494243.2	Gene:	ZK1240.1 / 173589	WormBaseID:	WBGene00022866	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	371	Identity:	65/371 - (17%)
Similarity:	123/371 - (33%)	Gaps:	132/371 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LQNLLRCPKCSKCFTYLYNTNSEEDNHRPFLLGCGHTLCESC----LWNDRLDPKCAVCHSPAPP 80
            :..::.|..|:..|      :|..::..|.:|.|||::|:.|    |.|..:  .|..|.
Worm     1 MSKVIECEICNLEF------SSVNEDQVPRILKCGHSVCQCCATKLLKNSAI--SCPFCR----- 52

  Fly    81 TIVAKRSDCKSVANLRDLYELNYHVLGRTSSLSYLLPFAKDSANQSLSPSSISEIVQTVKCSECG 145
                   :..||:.::|| :.|:.:|                        .|.|..:|.:..|..
Worm    53 -------ETTSVSAVKDL-QKNFALL------------------------QIIEHTKTERVEEED 85

  Fly   146 NATASGECRQCNAFYCRRCFDAVHKRSRVLKSHIFRNSTEQDSSFSKKLRVGDQYFTLPSQNLCI 210
            .|....:|             |.||.:.                               ::.:|:
Worm    86 EADVPPKC-------------ATHKYNM-------------------------------AEFVCL 106

  Fly   211 HHRMPKDKYCMKCYRSHCQICSTVH-HSGH----------RIRKLIE----INQSYASEIPTTLN 260
                  |..|....:..|:.|.... |:||          ::|.|::    .::....:|...:.
Worm   107 ------DPNCSSDEKLMCRTCEEFGVHAGHSKGLLQTEALKLRTLLKDKLLKSEDQIVQIDKNIE 165

  Fly   261 SLNMA-HIHVLNGKQVVQRAKQKLNDYATETLASISKRFSHLHGLLQVAELQVIEKLRE----SS 320
            .::.| ..:.::|| |.|..|..::.|           ::.:...|...|....:||||    :|
Worm   166 EVDSAQQTNQVDGK-VFQDKKDLISVY-----------YTSIRETLDAQEALANQKLREIAESNS 218

  Fly   321 LPPQLKLNEAMGQLSGYETVIERLTKSLNSGVGNDMAVPRDVSLRW 366
            ...:|.|.|....|...:...|:|...|.....:.:|:..::.| |
Worm   219 ASNKLLLEELSESLETQKLKNEKLKSFLGMSNADLLALNSEIQL-W 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..75	CDD:291308	14/53 (26%)
		BBOX	139..174	CDD:197662	6/34 (18%)
		TUDOR	536..648	CDD:278965
		TUDOR	741..859	CDD:278965
		TUDOR	<805..839	CDD:119391
		TUDOR	981..1107	CDD:278965
		TUDOR	1296..1403	CDD:278965
		TUDOR	1337..1385	CDD:119391
		TUDOR	1710..1761	CDD:119391
ZK1240.1	NP_494243.2	RING_Ubox	4..53	CDD:388418	15/68 (22%)
		modified RING-HC finger (C3HC3D-type)	7..51	CDD:319361	14/51 (27%)
		Zinc_peptidase_like	<56..>184	CDD:387401	31/203 (15%)
		Bbox2_TRIM23_C-IX_rpt2	89..139	CDD:380832	12/99 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D69831at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010