Protein Alignment qin and Tdrd15

DIOPT Version :10

• Sequence 1: NP_650735.3
• Gene: qin / 42236
• FlyBaseID: FBgn0263974
• Length: 1857
• Species: Drosophila melanogaster
• Sequence 2: XP_006239938.1
• Gene: Tdrd15 / 102556253
• RGDID: 7716193
• Length: 2015
• Species: Rattus norvegicus
• Alignment Length: 2084
• Identity: 413/2084 - (19%)
• Similarity: 667/2084 - (32%)
• Gaps: 696/2084 - (33%)

  Fly   202 TLPSQNLCIHH--RMPKD---KYCMKCYRSHCQICSTVHHSGHRIRKLIEINQSYASEIPTTLNS 261
            ||...:|.:.|  .:|||   |:..| ..|.||.      ..|.:::.|:.       ||...|:
  Rat     9 TLLDADLTVLHIECLPKDILVKFQGK-NNSECQF------DYHILQREIQY-------IPKVANN 59

  Fly   262 LNMAH---IHVLNGKQVVQRAKQKLNDYATETL--------------ASISKR---------FSH 300
            |.:..   :....|:....|...|.|:..|..|              ||..|:         |..
  Rat    60 LGIDEFCLVEERTGEWQRGRVLGKKNEVYTVLLIDRGDELTVDSTRVASAYKKIFELPPRVIFGI 124

  Fly   301 LHGLLQVAE------LQVIEKL--------RESSLPPQLKLNEAMGQLSGYETVIERLTKSLNSG 351
            ...:|.|.|      |.....|        .::.||.|:.|.||...:||   |:|     |..|
  Rat   125 FANILPVGEKWSPKALNYFRSLVGIQLKGNMQTILPLQMILLEAPKVISG---VLE-----LQLG 181

  Fly   352 VGNDMAVPRDVSLRWLLKLICEHLEKIPTTVQVSKVDENPYRVTCSRFMDISNIFKCEFVNPNIQ 416
                ..|.||.     .:||.|.|::||..:......:.|...:.|:...:...:..:...|::.
  Rat   182 ----RFVDRDT-----FRLIVETLKEIPQPMPDLLRHKRPVLQSRSKSTSLDMQYVLDNFQPSLP 237

  Fly   417 VCFKTDLEISRSLSSS----------PKGEITFLT------------SSSSSKENF--------- 450
            |.....:::|.:||.|          |  |:..||            .:|.:.|||
  Rat   238 VGSLDSIKVSSALSPSKFYCQLLKQIP--ELEDLTERMNLHYDTGDQENSPACENFGLLCVAKGT 300

  Fly   451 DPHSRKLLLAQ---------------------NSKLKKATQ-----------------VSQSQKK 477
            :...::.:|.|                     :..:||..|                 .|..|:.
  Rat   301 NGRWQRGILQQVLPDNQVKIWFMDYGGSESVPSVHVKKLKQDFVFAPLFSFPCSLTYLHSPDQEV 365

  Fly   478 RGKNATEVAQSSL-NSTAAIIDEFPAKD------LDFLHNFSSLDITKRNKTTE----------- 524
            |.:..|...|:.| :..:|.||.|...:      |....:.:.....:|.::|:
  Rat   366 RKQQLTVFKQALLGHVVSACIDCFSEDERLYYVTLQPQESAAHAKCLQRTRSTQIHCPAFEPDIS 430

  Fly   525 ---DSSDWFKTDTLV-----------------------------------RVRSVQSPEDFYVQG 551
               |.:..::||:.|                                   .|.:|.:|.:|:|:
  Rat   431 KALDDAGTYRTDSFVVDVQQPAGGLNKEDDLRAAFAIKTVKMEIESTYIAFVVNVLNPSNFWVR- 494

  Fly   552 IHAAQRLREELDTFAHTLSDSSSVP-----------PTIVVGQNYIIHHKDKDR-YYRALVSQKL 604
               ..:.:.:......|::...:.|           |.:.....|     .||| :|||::::
  Rat   495 ---INKYQNKFQDLMRTINMFYNKPENDELTLRHPGPGLFCCARY-----SKDRCFYRAIITE-- 549

  Fly   605 TNENLYNVFLTDIGVHLHVRCSDFRVVPERISHLPYSAVHCSLSELMPKNGESEWDSKASAFLKQ 669
            .::...||:|.|.|....:...|.:::......||..||||||:.:.|..  ..|...|:.:.|:
  Rat   550 VDDYRINVYLLDYGSTHSISLFDAKILLPEFCELPPLAVHCSLAYIAPVT--KVWIKAATDYFKK 612

  Fly   670 IVQNNPV--RVIVKKALTY---------------------------------------------- 686
            ||.|..:  :||.|:...|
  Rat   613 IVLNKAILLQVIRKRDDKYMVNIQNVEAPENTDAVSLMLQAGHAKPAEVPSSGFHKSVRDRLVLK 677

  Fly   687 --ELHGVDLITS---------NYDT-----NISVRDSFLYCGLAISRDGAPLWLPPAPTALRLPR 735
              .||...::||         .|.:     |||....||  .|.:|.:   |...|.|:. ....
  Rat   678 LNTLHEKSVVTSVPVKRPEPERYHSNKLKGNISSLCRFL--DLKVSFN---LVFEPNPSQ-SYKE 736

  Fly   736 ISFRFGDVYMVQMLHVEDPQEFYVMRHDYEKKRLWLQFSLQEAMDRINISQLQNIFLGQLH---- 796
            ..|:.|.:..|...:...|.:|...          ||..|::.  ::.:.|:|..:  .:|
  Rat   737 YVFKPGKLLEVNCSYCHGPGDFSCQ----------LQCKLEDL--KLLMEQIQAYY--SIHPEPY 787

  Fly   797 ----LGCVLQSG--GQWKRASIEQILPDGYVLVHLVDEGPSQKVFWDQLFVLPQKFWD-TGLAIK 854
                :.||.:..  |:|.||:|.....:..|.:..||.|..::||...|..:...|.. ...|.:
  Rat   788 QTGKVACVAKHSRDGKWYRAAILTQASEQEVELIFVDYGNQERVFIKDLCAINPHFLALEAQAFR 852

  Fly   855 CCLAD-VETRAEHSYTWTPEGTTLFKQLTSNPRLYMDVISCTEDLVY--VSLH------FERSNS 910
            |||.. ||........||.|.:..|....|:   ...:::|   :||  |.:|      .....|
  Rat   853 CCLNYLVEPITYKLLDWTAEASRDFGNFISS---CGGLLTC---IVYALVLIHPRCLCNLVDLQS 911

  Fly   911 ETTSVGVQLVAHGHCTSSGESSRMITPTVSNRSVRFDEETKKFIAQQKVRPVELSPYRMPDNTER 975
            ..||....|:..| .|.....||.:..::|..|..:.....|..:::
  Rat   912 PFTSANEFLLRRG-STHHSAFSRPLPFSISLYSYYYSSFDVKIGSEE------------------ 957

  Fly   976 NKRTTVNILYVRKPDEFYVTLPHFQKAINNLQKSVQKAAAAMYQNMLPRTDWQVGDMCYARVQAN 1040
                .|.|.:|..|..||..|....|.:..|:..:.:   .:...|..:.||....:|.::.
  Rat   958 ----DVYISHVYSPKRFYCQLCRNSKDLEMLETRITE---MINLKMCSKYDWNRMRLCISQY--- 1012

  Fly  1041 CDSQALWYRGVVTGVIPPGITCPIVRYQVHLRDLG--ELIDDVHSSSLANIDEADMRISSSAKRC 1103
             ....|.||.:|........||      |:..|.|  :|:.:....::::.....:.....|.:|
  Rat  1013 -IEDGLSYRALVKPTASASDTC------VYFVDYGNEQLVKENMLCAISDQFPELLFTPMQAIQC 1070

  Fly  1104 HLHGIRPIG-----DEWSKD--------------------AIDFF-----MDQ-----LKAYNEI 1133
            .|..:|.|.     :.|.:|                    .||.:     ::|     |..|.|.
  Rat  1071 FLSDLRDIDIPGEINRWFEDNFLGKPLKAVILSRESDGQLGIDLYDGYQHINQTIKLLLNVYGEK 1135

  Fly  1134 H-----VTGRGRTENSLSVILWGSLSILTGPFSPATIKYVNINKALLMAGMAEKDHNSDSEDDQQ 1193
            |     ..|:.:..|.:|.:   ||...|    .:...:..|||..|....|.|       .|:.
  Rat  1136 HSKQAWCVGKNQRLNRVSAV---SLKENT----ESKRCHNAINKTSLATHPANK-------TDRW 1186

  Fly  1194 SMPENV---SVNSEEAAKANDWESCLSKIDGTSKTNDSLNLIESRSVTVGFEHNEDMPPLA---- 1251
            ..|:::   |:.|....|......  ||:..:||  |.|..|:..:.:|....:.|..|.:
  Rat  1187 MRPQSIYSRSLKSSVCCKVEPMPK--SKVKKSSK--DRLKNIKFAAGSVHIPEDSDTGPNSEERV 1247

  Fly  1252 ---LLEDLGNTKNTTGET--TPPAGWTTRRKCDKSVFTAIATNVTYECCIYLTLASDKPFIEHMG 1311
               |.:||..:...:.:.  .||.....:...|.|.                .:....|.|.|..
  Rat  1248 SKLLTKDLNQSAPQSPQVLIRPPITDIPQTHIDLST----------------QIKGSAPTIHHPA 1296

  Fly  1312 NLLV------REYKPLMDKQKERSTSYTYKVGQAVVVTYHM----DNMIYRGIVQR-LENNHNEY 1365
            |..:      .|...|.|..||::.|...:....::|..|.    |:...||:.:. |.....|.
  Rat  1297 NFHMASTENGNEATELTDVLKEKTDSQKNRNCLTLLVRDHAEYGNDHATSRGVTKNVLAEGSFEV 1361

  Fly  1366 TVYYVDYGNMELVKAD-------EMLPYAPFPDLNAMCFLVELHGVR---------SKQGKYSLK 1414
            .|:  |:||..:|...       |:|   ..|.|....|   ||.||         ||...|...
  Rat  1362 EVF--DHGNTAIVNGSKVYSINRELL---TIPRLGIGSF---LHRVRWDGPIEICKSKIANYFAS 1418

  Fly  1415 EMDTVHLNLVMKLSGVRIVDDETVGPNKIPKCQIK------------------------------ 1449
            .|.......|.|....:...:.|.|    .||.||
  Rat  1419 VMKGTVFCEVWKTPDQKWEVNITCG----DKCVIKKLLRWSPCPKPQKLALQMPQAISHKVSPHE 1479

  Fly  1450 -----VGNVDIATMMIDSGMSVPI----------------EKQTIKNNTKYL-PSQKF---LEDF 1489
                 .|.|::.      |.|:|.                .:|..::.|.|: .:.||   |.:.
  Rat  1480 ADNERTGRVNMC------GGSMPFLPFSQQLGENPFELLRHEQLEESKTIYISETGKFHVTLPEN 1538

  Fly  1490 KVFDELDHLAAGEGELSDKEAPPTQRKHDSISSVQQ-PPTKKFLVDQEEVEAFECDQDFDCQQAA 1553
            :...:|..|.|..||:              |||.:: .|.|.|......:|...|
  Rat  1539 QKTSDLALLKAPSGEI--------------ISSPRRGVPYKCFWFTHSTLEFIVC---------- 1579

  Fly  1554 QKMHLNNNFYLGDFGKYADETTARDEDEPHSNSSKSIDMEV-------FANVNDSQLEPLNSFAT 1611
            ...||..:..   ..||:|.|.             .:|:.|       ..||..||:|
  Rat  1580 LFAHLEMSIL---SLKYSDYTW-------------EVDLLVNGLLPLGCLNVATSQVE------- 1621

  Fly  1612 EQLIRR-----IALRQQEIKDSITFSPIDTSSVRSFYDASASFKTLSLPNGVKEFYCTVDNVLSD 1671
            ||..:|     ..|..|.:....|..|       |.:....:.|..|   |:....|.    |||
  Rat  1622 EQRKQRSSGTVFGLEPQTLWSPCTILP-------SVWPLLQNGKRYS---GIATAVCD----LSD 1672

  Fly  1672 TELQIAPCLSEFTKHEISLIQETSTLIKDA-EPL-------MEPKVGDLCLARYSRDKQWYRANI 1728
            ..:|    |.:|    ..:::...||:.|. |||       |.|  |..||.:...:.:..||.|
  Rat  1673 FCVQ----LEDF----FDIMKHLFTLLSDVPEPLQALPSEHMIP--GSSCLFKSELEDRRSRAEI 1727

  Fly  1729 KEISP-----ILSPTSEQVTVFYIDFHDTEKVSFNHLKVMPSQLFMFPLRSFCVKLHGI--KRNK 1786
            .|:|.     :||.....|.|.|.:        ..:||.:|.::...|..|:...|:.:  ...|
  Rat  1728 SEVSDQSLHLVLSDLGRSVHVPYSE--------ATNLKSVPQKIMNLPRLSYPCGLYFVLPAMGK 1784

  Fly  1787 SFKEKSVRQALQACLCQHPLVFARVHYPLNYYPNRPNC--DADLIEVELYEN------------- 1836
            .:..: |||..|.|..:..||       :.:..|.|..  :.|:|:    ||
  Rat  1785 LWTNE-VRQLFQDCRSKPGLV-------IQFRENGPGAVSEVDVIQ----ENDSVADTLVASGLA 1837

  Fly  1837 RHEK 1840
            ||.|
  Rat  1838 RHPK 1841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..76	CDD:434085
		Bbox1	140..178	CDD:380815
		Bbox2	208..244	CDD:380814	11/40 (28%)
		TUDOR	536..648	CDD:425754	29/158 (18%)
		TUDOR	742..859	CDD:425754	28/127 (22%)
		Tudor_SF	989..1139	CDD:470623	35/191 (18%)
		TUDOR	1296..1403	CDD:425754	28/124 (23%)
		TUDOR	<1703..1781	CDD:425754	23/89 (26%)
Tdrd15	XP_006239938.1	Tudor_TDRD15_rpt1	14..159	CDD:410507	31/158 (20%)
		Tudor_TDRD15_rpt2	238..356	CDD:410508	18/119 (15%)
		Tudor_SF	472..612	CDD:470623	32/152 (21%)
		Tudor_SF	734..858	CDD:470623	30/137 (22%)
		Tudor_SF	949..1072	CDD:470623	26/157 (17%)
		Tudor_SF	1295..1399	CDD:470623	26/111 (23%)
		Tudor_SF	1660..1795	CDD:470623	40/160 (25%)