Protein Alignment qin and Tdrd7

DIOPT Version :10

• Sequence 1: NP_650735.3
• Gene: qin / 42236
• FlyBaseID: FBgn0263974
• Length: 1857
• Species: Drosophila melanogaster
• Sequence 2: NP_001277404.1
• Gene: Tdrd7 / 100121
• MGIID: 2140279
• Length: 1119
• Species: Mus musculus
• Alignment Length: 1026
• Identity: 196/1026 - (19%)
• Similarity: 328/1026 - (31%)
• Gaps: 340/1026 - (33%)

  Fly   311 QVIEKLRESSLPPQLKLNEAMGQLSGYETVIERLTKSLNSGVGNDMAVPRDVSLRWLLKL----- 370
            |.:||  .:..||....|    ::...:..|:.:....|:|:             |:.||
Mouse   239 QTVEK--PNITPPASYTN----KMDEVQNRIKEILDKHNNGI-------------WISKLPHFYK 284

  Fly   371 ----------ICEHLEKIPTTVQVSKVDENPYRVTCSRFMDISNIFKCEFVNPNIQVCFKTDLEI 425
                      :.:..|..|....|.|        .|....| |.::......|     .|:|.:.
Mouse   285 EFYKEDLNQGVLQQFEHWPHICTVEK--------PCGGGQD-SLLYPARREQP-----LKSDQDP 335

  Fly   426 SRSLSSSP-------------------KGEITFLTSSSSS---------------KENFDPHSRK 456
            .:.|...|                   |.::..|....||               |..| |....
Mouse   336 EKELPPPPPAPKQEVPSQGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKF-PEDAL 399

  Fly   457 LLLAQNSKLKKATQVSQSQKKRGKNATEVAQSSLNSTAAIIDEFPAK-DLDFLHNFSSLDITKRN 520
            ..||..|.:.....:|.:.:|    |...|:..|.:...:.||..|: |.| :.:....:..:..
Mouse   400 KNLASLSDVCTINYISGNTQK----AILYAKLPLPTDKILKDEGQAQGDFD-IKSMIEQEYLQIE 459

  Fly   521 KTTEDSSDWFKTDTLVR---VRSVQSPEDFYVQ--------------GIHAAQRLREELDTFAHT 568
            |...:|:|.|..|..|.   :.:..||....|:              ...|||.|.|  |.....
Mouse   460 KNMAESADEFLEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQELME--DEMKEF 522

  Fly   569 LSDSSSVPP--TIVVGQNYIIHHKDKDRYYRALVSQKLTNENLYNVFLTDIGVHLHVRCSD-FRV 630
            .|.:..|.|  |:.|||...: :.::|.:.||.:..  |:||...|...|.|...::..|. :|:
Mouse   523 YSKNPRVTPIQTVHVGQLLAV-NAEEDAWLRAQIIS--TDENKIKVCYVDYGFCENIEKSKAYRL 584

  Fly   631 VPERISHLPYSAVHCSLSELMPKNGESEWDSKASA------FLKQIVQNNPVRVIVKKALTYELH 689
            .| |...|.:.|..|.|:.|...|.:.:......:      |..:|:..:.|.::|    .|:..
Mouse   585 NP-RFCSLSFQATKCKLAGLEVLNDDPDLVKAVESLTCGKIFAVEILDKSDVPLVV----LYDTS 644

  Fly   690 GVDLITSNYD--------------------TNISV----RDSFLYC-----GLAISRDGAPLWLP 725
            |.|.|..|..                    ||:.|    .|..|||     ||....|
Mouse   645 GEDDININATCLKAICDRSLQVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLND------- 702

  Fly   726 PAPTALRLPRISFRFGDVYMVQMLHVEDPQEFYVMRHDYEKKRLWLQFSLQEAMDRINISQLQNI 790
                                  :||  ..::::..:|...:..:.|.
Mouse   703 ----------------------LLH--KTEDYFHCKHMTSEYFISLP------------------ 725

  Fly   791 FLGQLHLGCVLQSGGQWKRASIEQILPDGYVLVHLVDEGPSQKVFWDQLFVLPQKFWDTGL---- 851
            |.|::   |:....|:|.|..|..:.....:.|..:|.|.|..|...:|..:|.:|....|
Mouse   726 FCGKI---CLFHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPP 787

  Fly   852 -AIKCCLADVETRAEHSYTWTPEGTTLFKQLTSNPRLYMDVISC------------TEDLVYV-- 901
             ||||||||:   .:....|||:.....:.         .|::|            |:.:.||
Mouse   788 QAIKCCLADL---PQSIGMWTPDAVLWLRD---------SVLNCSDCSIKVTKMDETKGVAYVYL 840

  Fly   902 -----------SLHFERSNSE---------TTSVGVQLVAHGHCT-------SSGESSRMITPTV 939
                       |::.:.:|::         .::|.....:.|:..       |..||.|...|.|
Mouse   841 FTPNNFPDPHRSINRQITNADLWKHQKDVFLSAVSTAASSPGNRNGGTPAPGSPAESLRKSHPEV 905

  Fly   940 SNRSVRFDEETKKFIAQQKVRPVELSPYRMPDNTERNKRTTVNILYVRKPDEFYVTLP------H 998
            ..:||.  :.|..|..::...||.||                     |..:...|.:|      |
Mouse   906 IKKSVL--DHTSSFSLEELPPPVHLS---------------------RSGEHMDVYVPVACHPGH 947

  Fly   999 F----QKAINNLQKSVQKAAAAMYQNMLPRTDWQV-GDMCYARVQANCDSQALWYRGVVTGVIPP 1058
            |    .:.|:.|:..:::  ..:|.::.......| .|..||....|     .|||.::.|::..
Mouse   948 FVIQPWQEIHKLEVLMEE--MILYYSVSEERHIAVERDQVYAAKVEN-----KWYRVLLKGILTN 1005

  Fly  1059 GITCPIVRYQVHLRDLGELIDDVHSSSLANIDEAD------MRISSSAKRCHLHGIRPIGDEWSK 1117
            |:.      .|:..|.|:       ..|.||.:..      .::...|....|.|::  ..:||:
Mouse  1006 GLV------SVYELDYGK-------HELVNIRKVQPLVDVFRKLPFQAVTAQLAGVK--CSQWSE 1055

  Fly  1118 DAIDFFMDQLKAYNEIHVTGRGRTENSLSVILWGSLSILTGPFSPATIKYV 1168
            :|...|              |...|....|.|..::...|.|:....:.|:
Mouse  1056 EASMVF--------------RNHVEKKALVALVQTVVEHTNPWDRKVVLYL 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
qin	NP_650735.3	zf-RING_5	25..76	CDD:434085
		Bbox1	140..178	CDD:380815
		Bbox2	208..244	CDD:380814
		TUDOR	536..648	CDD:425754	33/131 (25%)
		TUDOR	742..859	CDD:425754	26/121 (21%)
		Tudor_SF	989..1139	CDD:470623	30/166 (18%)
		TUDOR	1296..1403	CDD:425754
		TUDOR	<1703..1781	CDD:425754
Tdrd7	NP_001277404.1	LOTUS_1_TDRD7	38..124	CDD:193600
		LOTUS_2_TDRD7	256..322	CDD:193587	13/87 (15%)
		LOTUS_3_TDRD7	361..425	CDD:193588	13/68 (19%)
		Tudor_SF	513..610	CDD:470623	29/102 (28%)
		Tudor_TDRD7_rpt2	674..813	CDD:410499	41/193 (21%)
		Tudor_TDRD7_rpt3	951..1041	CDD:410500	19/109 (17%)