Protein Alignment Tssk and NUAK1

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_055655.1
• Gene: NUAK1 / 9891
• HGNCID: 14311
• Length: 661
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 90/287 - (31%)
• Similarity: 147/287 - (51%)
• Gaps: 27/287 - (9%)

  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKII--DKAKAPTDFVNKFFPRELEILTKIDHSN 90
            |.:...:|:|:|..|   ..|.:...|..:|.|.|  ||.|...|.|:  ..||:||::.::|.:
Human    55 YELQETLGKGTYGKV---KRATERFSGRVVAIKSIRKDKIKDEQDMVH--IRREIEIMSSLNHPH 114

  Fly    91 IIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDL 155
            ||.|:.:.:...||.|.|.||..|:|..:|.....:.|::::.:|.|:..|:.|.|...:.||||
Human   115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDL 179

  Fly   156 KCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLG 220
            |.|||||....|||:||||.:...:.|.    ..:|:|||..||:||:|.||||.....|:|:||
Human   180 KLENILLDDNCNIKIADFGLSNLYQKDK----FLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG 240

  Fly   221 VILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREI 285
            |:|:.::...||||..:...|:     |:.:.....:.|..:.|:..:..:|......|..:.:|
Human   241 VLLYTLVYGTMPFDGFDHKNLI-----RQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDI 300

  Fly   286 LNCAWLR-----------TVEESQTPI 301
            .|..|:.           .:.:|::|:
Human   301 ANHWWVNWGYKSSVCDCDALHDSESPL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	87/264 (33%)
NUAK1	NP_055655.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		STKc_NUAK	53..306	CDD:270975	87/264 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	345..421
		GILK motif	399..402
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	442..570