Protein Alignment Tssk and NPR1

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_014216.1
• Gene: NPR1 / 855538
• SGDID: S000005127
• Length: 790
• Species: Saccharomyces cerevisiae
• Alignment Length: 369
• Identity: 90/369 - (24%)
• Similarity: 144/369 - (39%)
• Gaps: 93/369 - (25%)

  Fly    14 GTRSSDVDALAQRGYNVGH-KIGEGSYATVITAGYAD---DHGHG-------------------- 54
            |:..|...|:....::..| ..|..||:|... |..|   .|.||
Yeast   384 GSPLSSGIAVPSHSHSSSHFAAGNNSYSTSYN-GNGDTIYSHSHGGSGIPFSKRYIKTGADLGAG 447

  Fly    55 ----VHLACKIID-KAKAPTDFVNKF-----------FPRELEILTKIDHSNIIQIHSILQRGPK 103
                |.||.:|.| |..|..:|..||           ...|..|.|.::|.|||:...|:....:
Yeast   448 AGGSVKLAQRISDNKIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDR 512

  Fly   104 IFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNI 168
            |...|.|.|. ||.: |..|..:..::....|.|:...::|||::.:||||||.:|.:::::..:
Yeast   513 ILQVMEYCEY-DLFA-IVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIV 575

  Fly   169 KLADFGFA---RYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAK 230
            ||.|||.|   .|....|  .:::....||..|.||||.....|||:..|.||..:|...|:..|
Yeast   576 KLIDFGAAVVFSYPFSKN--LVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKK 638

  Fly   231 MP-----------------------------------FDDSNLTKL---------LEDQRNRKFA 251
            .|                                   :|:|:.|:.         :.|..|....
Yeast   639 FPWKIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDESHSTEKKKPESSSNNVSDPNNVNIG 703

  Fly   252 FRRKLQETISAQAKATVSVLLEPEAHARWNLREILNCAWLRTVE 295
            .:| |..::..:.:..|..:::.....|.|:.||:...|:|:::
Yeast   704 PQR-LLHSLPEETQHIVGRMIDLAPACRGNIEEIMEDPWIRSID 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	85/350 (24%)
NPR1	NP_014216.1	Protein Kinases, catalytic domain	451..742	CDD:473864	75/295 (25%)