Protein Alignment Tssk and GIN4

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_010795.3
• Gene: GIN4 / 852119
• SGDID: S000002915
• Length: 1142
• Species: Saccharomyces cerevisiae
• Alignment Length: 276
• Identity: 92/276 - (33%)
• Similarity: 144/276 - (52%)
• Gaps: 27/276 - (9%)

  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKA------KAPTDFVNKFFP--------R 78
            :.:|..:|.||...|   ..|.:...|...|.|:|.||      .:.|..|....|        |
Yeast    19 WKLGETLGLGSTGKV---QLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIER 80

  Fly    79 ELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALK 143
            |:.|:..::|.|:::::.:.:....:::.:.|||.|:|.:.:...||:.|.::..:|.|:...:.
Yeast    81 EIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVS 145

  Fly   144 YLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRP 208
            |.|.|.|.|||||.||:||..:.|||:||||.|  ..:..|:.:  ||.|||..|||||:|.|.|
Yeast   146 YCHALGIVHRDLKPENLLLDHKYNIKIADFGMA--ALETEGKLL--ETSCGSPHYAAPEIVSGIP 206

  Fly   209 YDPKLADAWSLGVILFIMMNAKMPFD--DSNL-TKLLEDQRNRKFAFRRKLQETISAQAKATVSV 270
            |....:|.||.|||||.::..::|||  |.|: |.||:.|:..   |.....:.||.:|:..:..
Yeast   207 YQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGE---FEMPSDDEISREAQDLIRK 268

  Fly   271 LLEPEAHARWNLREIL 286
            :|..:...|...|:||
Yeast   269 ILTVDPERRIKTRDIL 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	92/276 (33%)
GIN4	NP_010795.3	Protein Kinases, catalytic domain	17..289	CDD:473864	92/276 (33%)
		Kcc4p_like_C	1026..1139	CDD:213379